摘要
目的探讨超声造影(CEUS)评价颈动脉硬化斑块内新生血管与急性脑梗死患者美国国立卫生研究院卒中量表(NIHSS)评分、改良Rankin量表(mRs)评分的关系。方法回顾性分析2016年10月—2019年10月南京医科大学附属淮安第一医院收治的148例急性缺血性脑梗死患者的临床资料。按照患者有无颈动脉粥样硬化斑块,将无斑块者纳为A组(41例);其余107例患者有斑块,均接受颈动脉CEUS,按照CEUS检查结果(斑块分级情况)将患者分为B组(稳定斑块,斑块分级为0~Ⅰ级,19例)和C组(易损斑块,斑块分级为Ⅱ~Ⅲ级,88例)。观察急性脑梗死颈动脉粥样硬化斑块患者两侧颈动脉斑块造影分级情况,分析三组NIHSS、mRs评分情况及其与颈动脉粥样硬化斑块内新生血管分级的相关性。结果颈动脉粥样硬化斑块患者两侧颈动脉斑块造影分级情况比较,差异无统计学意义(P>0.05)。A、B组NIHSS、mRs评分比较,差异无统计学意义(P>0.05);A、B组NIHSS、mRs评分低于C组,差异有统计学意义(P<0.05)。急性脑梗死患者NIHSS、mRs评分与颈动脉粥样硬化斑块内新生血管分级均呈正相关(r=0.448、0.406,均P<0.05)。结论CEUS评价颈动脉硬化斑块内新生血管与急性脑梗死患者NIHSS及mRs评分密切相关。
Objective To investigate the relationship between contrast-enhanced ultrasound(CEUS)evaluation of neovascularization in carotid atherosclerotic plaques and the National Institutes of Health stroke scale(NIHSS)score and the modified Rankin scale(mRs)score in patients with acute cerebral infarction.Methods The clinical data of 148 patients with acute ischemic cerebral infarction admitted to the Huai′an First Hospital Affiliated to Nanjing Medical University from October 2016 to October 2019 were retrospectively analyzed.According to the presence or absence of carotid atherosclerotic plaque,those without plaque were admitted to group A(41 cases).The other 107 patients had plaque and received CEUS.According to the results of CEUS(plaque classification),the patients were divided into group B(stable plaque,plaque classification of 0-Ⅰ,19 cases)and group C(vulnerable plaque,plaque classification ofⅡ-Ⅲ,88 cases).The both sides of angiography grade of carotid artery plaques in patients with acute cerebral infarction with carotid atherosclerotic plaque were observed,and the NIHSS and mRs scores of the three groups and their correlation with the grade of neovascularization in carotid atherosclerotic plaque were analyzed.Results Comparison of both sides of the angiographic grading of carotid artery plaques in patients with carotid atherosclerotic plaque showed no statistically significant difference(P>0.05).Comparison of NIHSS and mRs scores between groups A and B showed no statistically significant differences(P>0.05).NIHSS and mRs scores in groups A and B were lower than those in group C,and the differences were statistically significant(P<0.05).NIHSS and mRs scores in patients with acute cerebral infarction were positively correlated with the grade of neovascularization in carotid atherosclerotic plaque(r=0.448,0.406,all P<0.05).Conclusion CEUS evaluation of neovascularization in carotid atherosclerotic plaques is closely related to NIHSS and mRs scores in patients with acute cerebral infarction.
作者
黄慧
盛文伟
HUANG Hui;SHENG Wenwei(Ultrasonography Lab,Huai′an First Hospital Affiliated to Nanjing Medical University,Jiangsu Province,Huai′an223300,China)
出处
《中国医药导报》
CAS
2020年第29期73-76,共4页
China Medical Herald
基金
江苏省卫生计生委医学科研项目(H2018082)。
