摘要
目的比较卡贝缩宫素对预防双胎妊娠剖宫产产后出血的效果分析。方法采用回顾性分析2017年4月—2019年4月珠海市妇幼保健院双胎妊娠剖宫产568例患者。根据胎儿娩出后用药情况分为两组:研究组同时使用卡贝缩宫素及缩宫素,对照组仅使用缩宫素。比较两组孕妇手术时间、手术前后血红蛋白变化及手术出血量,孕妇额外用药及不良反应情况。结果研究组术中额外用药率为22.1%,明显低于对照组40.4%,差异有统计学意义(P<0.05)。研究组手术前血红蛋白(121.6±1.2)g/L,对照组(119.1±1.3)g/L,两组比较差异无统计学意义(t=1.050,P>0.05)。研究组手术后血红蛋白(119.2±1.9)g/L,对照组(115.1±1.5)g/L,两组比较差异无统计学意义(t=1.510,P>0.05)。研究组术中出血量(831±255)mL,对照组(935±393)mL,差异有统计学意义(t=24.310,P<0.05);术后2 h出血量研究组(892±138)mL,对照组(1175±203)mL,差异有统计学意义(t=32.310,P<0.05);术后24 h出血量研究组(911±125)mL,对照组(1301±191)mL,差异有统计学意义(t=34.820,P<0.05)。结论卡贝缩宫素预防双胎妊娠剖宫产产后出血及减少术中额外使用宫缩剂的效果较显著。
Objective To compare the effect of carbetocin on preventing postpartum hemorrhage after cesarean section in twin pregnancy.Methods A retrospective case study was used to analyze 568 cases of cesarean section with twin pregnancy in Zhuhai Maternal and Child Health Hospital from April 2017 to April 2019.The fetuses were divided into two groups according to their medications after delivery:the study group used carbetocin and oxytocin at the same time,and the control group only used oxytocin.The operation time,hemoglobin changes before and after the operation,the amount of blood loss during the operation,the additional medication and adverse reactions of the pregnant women were compared between the two groups.Results The extra medication rate in the study group was 22.1%,which was significantly lower than the control group 40.4%,the difference was statistically significant(P<0.05).The preoperative blood hemoglobin in the study group was(121.6±1.2)g/L,and the control group was(119.1±1.3)g/L.There was no statistically significant difference between the two groups(t=1.050,P>0.05).The blood and postoperative hemoglobin of the study group was(119.2±1.9)g/L,and the control group was(115.1±1.5)g/L.There was no statistically significant difference between the two groups(t=1.510,P>0.05).Intraoperative blood loss study group was(831±255)mL,control group(935±393)mL,the difference was statistically significant(t=24.310,P<0.05);2 h postoperative blood loss study group was(892±138)mL,control group(1175±203)mL,the difference was statistically significant(t=32.310,P<0.05);24 h postoperative blood loss was(911±125)mL in the study group,(1301±191)mL in the control group,the difference was statistically significant(t=34.820,P<0.05).Conclusion The Carbetocin has a significant effect on preventing postpartum hemorrhage after cesarean section in twin pregnancy and reducing the additional use of uterine contractors during surgery.
作者
金萍
JIN Ping(Department of Obstetrics,Zhuhai Maternal and Child Health Hospital,Zhuhai,Guangdong Province,519000 China)
出处
《中外医疗》
2020年第28期1-3,8,共4页
China & Foreign Medical Treatment
关键词
产后出血
缩宫素
卡贝缩宫素
双胎妊娠
剖宫产
Postpartum hemorrhage
Oxytocin
Carbetocin
Twin pregnancy
Cesarean section
