摘要
目的探讨替米沙坦联合氨氯地平治疗高血压的临床效果。方法选择2018年7月至2019年6月医院收治的71例高血压患者为研究对象,根据随机数字表法将其分为A组(n=35,替米沙坦+美托洛尔)和B组(n=36,替米沙坦+氨氯地平)。比较两组患者的血压、不良反应发生情况及用药依从性。结果治疗后,两组的舒张压及收缩压均较治疗前显著降低,且B组低于A组(P<0.05)。B组的不良反应总发生率低于A组(P<0.05)。B组按时用药、按量用药的患者占比均高于A组(P<0.05)。结论替米沙坦联合氨氯地平治疗高血压,不仅能够达到良好的降压效果,而且能够减少不良反应的发生,提高患者的用药依从性,值得临床推广应用。
Objective To explore the clinical effect of telmisartan combined with amlodipine in the treatment of hypertension.Methods Seventy-one patients with hypertension admitted in the hospital from July 2018 to June 2019 were selected as the research objects and divided into group A(n=35,telmisartan+metoprolol)and group B(n=36,telmisartan+amlodipine)according to random number table method.Blood pressure,adverse reactions and medication compliance of the two groups were compared.Results After treatment,the diastolic blood pressure and systolic blood pressure in two groups were significantly lower than those before treatment,and those in the group B were lower than the group A(P<0.05).The total incidence of adverse reactions in the group B was lower than that in the group A(P<0.05).The proportions of patients who took drugs on time and in doses in the group B were higher than those in the group A(P<0.05).Conclusion Telmisartan combined with amlodipine in the treatment of hypertension can not only achieve good antihypertensive effect,but also can reduce the occurrence of adverse reactions and improve the medication compliance of patients,which is worthy of clinical promotion and application.
作者
邓锦松
DENG Jinsong(Dongguan Fenggang Hospital,Dongguan 523681,China)
出处
《临床医学研究与实践》
2020年第32期74-75,共2页
Clinical Research and Practice
