摘要
目的观察3D动脉自旋标记(3D ASL)、弥散张量成像(DTI)联合常规MRI鉴别诊断颅内血管外皮细胞瘤(HPC)与血管瘤型脑膜瘤(AM)的价值。方法回顾性分析经手术病理证实的15例HPC(HPC组)与11例AM(AM组),分析2组临床表现、MRI(包括平扫、增强、DTI、3D ASL)征象及功能成像参数差异。结果HPC组平均脑血流量(CBF)及各向异性分数(FA)均低于AM组(t=-8.99,P<0.01;t=-3.66,P<0.01),表观弥散系数(ADC)高于AM组(t=2.61,P=0.02);HPC组高灌注区和低灌注区CBF均低于AM组(t=-15.13,P<0.01;t=-8.30,P<0.01);HPC组平均发病年龄低于AM组(t=-2.39,P=0.02),性别差异无统计学意义(χ^2=1.69,P=0.19);相比AM组,HPC组更易出现分叶征(χ^2=9.09,P<0.01)及囊变坏死(χ^2=9.38,P<0.01),HPC病灶T1WI以等高信号为主(χ^2=27.78,P<0.01)、T2WI以等低信号为主(χ^2=16.33,P<0.01),瘤周水肿程度轻(χ^2=19.25,P<0.01),血管流空影更常见且更粗大(χ^2=9.02,P=0.01),多与硬脑膜多为窄基底相连(χ^2=28.54,P<0.01)而脑膜尾征少见(χ^2=25.00,P<0.01)。结论HPC与AM的MRI征象及各功能成像参数值存在一定差异,可为鉴别诊断提供参考。
Objective To explore the value of 3 D arterial spin labeling(3 D ASL)and diffusion tensor imaging(DTI)combined with conventional MRI in differential diagnosis of hemangiopericytoma(HPC)and angiomatous meningioma(AM).Methods Data of 15 cases of HPC(HPC group)and 11 cases of AM(AM group)confirmed by postoperative pathology were retrospectively analyzed.The clinical data,MRI(including plain and enhanced scanning,DTI and 3 D ASL)findings and functional imaging parameters were analyzed between two groups.Results The mean cerebral blood flow(CBF)and fractional anisotropy(FA)in HPC group were all lower than those in AM group(t=-8.99,P<0.01;t=-3.66,P<0.01),and the apparent diffusion coefficient(ADC)in HPC group was higher than that in AM group(t=2.61,P=0.02).CBF of high perfusion area and low perfusion area were also lower in HPC group than that in AM group(t=-15.13,P<0.01;t=-8.30,P<0.01).The mean age of onset was lower in HPC group than in AM group(t=-2.39,P=0.02).Lobulated sign(χ^2=9.09,P<0.01),tumor cystic necrosis(χ^2=9.38,P<0.01),mainly iso-hyperintense signals on T1 WI(χ^2=27.78,P<0.01)and iso-hyperintense signals on T2 WI(χ^2=16.33,P<0.01),mild extent of peritumoral edema(χ^2=19.25,P<0.01),dilated blood flow void(χ^2=9.02,P=0.01),narrow base with dura mater(χ^2=28.54,P<0.01)and seldom on dural tail sign(χ^2=25.00,P<0.01)were more common in HPC group than in AM group.No significant difference of patients’gender was found between HPC group and AM group(χ^2=1.69,P=0.19).Conclusion There were some differences of MRI features and functional imaging parameters between HPC and AM,which could provide references for differential diagnosis of these two diseases.
作者
胡瑞
吴奕君
陈文
郑克华
王代忠
徐霖
HU Rui;WU Yijun;CHEN Wen;ZHENG Kehua;WANG Daizhong;XU Lin(Department of Radiology,Taihe Hospital,Hubei University of Medicine,Shiyan 442000,China;Department of Pathology,Taihe Hospital,Hubei University of Medicine,Shiyan 442000,China)
出处
《中国医学影像技术》
CSCD
北大核心
2020年第10期1446-1450,共5页
Chinese Journal of Medical Imaging Technology
基金
十堰市太和医院院级项目(2020JJXM063)。
关键词
血管外皮细胞瘤
脑膜瘤
诊断
鉴别
磁共振成像
hemangiopericytoma
meningioma
diagnosis,differential
magnetic resonance imaging
