摘要
目的分析初孕育龄女性孕前促甲状腺激素(TSH)水平对自然流产发生风险的影响。方法选取周口市妇幼保健院2018年1月—2019年12月收治的出现自然流产的初孕育龄女性100例,将其作为实验组;并选取收治的正常活产的初孕育龄女性300例,将其作为对照组;对两组女性的基线特征进行观察比较,通过多因素Logistic回归模型对孕前TSH水平对自然流产发生风险的影响进行分析。结果在年龄、民族、职业、户口所在地、高血压等资料方面,对照组与实验组比较差异有统计学意义(P<0.05)。实验组与对照组的TSH水平升高率、正常高值率、降低率比较差异有统计学意义(P<0.05)。Logistic多因素回归分析结果显示,TSH水平升高组的自然流产风险明显高于孕前TSH水平正常组,比较差异有统计学意义(P<0.05);TSH水平正常高值组与TSH水平降低组的自然流产风险比较差异无统计学意义(P>0.05)。结论初孕育龄女性的孕前TSH水平上升可能会导致自然流产的发生风险增加,如果初孕育龄女性的孕前TSH水平上升则应在孕前严格检测甲状腺功能指标。
Objective To analyze the effect of TSH level on the risk of spontaneous abortion.Methods From January 2018 to December 2019, Totally 100 women of first pregnancy and childbearing age who had spontaneous abortion in our hospital were selected as the experimental group;300 women of first pregnancy and childbearing age who had normal live birth were selected as the control group;The baseline characteristics of the two groups of women were observed and compared, and the impact of TSH level on the risk of spontaneous abortion before pregnancy was analyzed by multi factor Logistic regression model Sound analysis.Results There were significant differences between the control group and the experimental group(P<0.05). Compared with the control group, there were significant differences in the increase rate, normal high value rate and decrease rate of TSH between the experimental group and the control group(P<0.05). Logistic regression analysis showed that the risk of spontaneous abortion in the group with high sh level was significantly higher than that in the group with normal TSH level before pregnancy(P<0.05);There was no statistical significance between the group with high TSH level and the group with low TSH level(P>0.05).Conclusion The increase of TSH level before pregnancy may increase the risk of spontaneous abortion. If the TSH level before pregnancy increases, the thyroid function should be tested strictly before pregnancy.
作者
王娜
WANG Na(Zhoukou Maternal and Child Health Hospital,Zhoukou,Henan 466000,China)
出处
《医药论坛杂志》
2020年第10期79-81,85,共4页
Journal of Medical Forum
关键词
初孕
育龄女性
孕前
促甲状腺激素
自然流产
发生风险
First pregnancy
Women of childbearing age
Pre pregnancy
Thyrotropin
Spontaneous abortion
Risk of occurrence
