摘要
目的:采用磁共振心肌特征追踪技术评价扩张型心肌病(DCM)患者左心室心肌应变力的变化规律。方法:连续性搜集本院近两年确诊为DCM的60例患者的病例资料,同时选择健康成年对照组76例,获得左心室全局径向峰值应变(GPRS)、全局纵向峰值应变(GPLS)、全局周向峰值应变(GPCS)及左心室射血分数(LVEF)。比较患者与对照组间左心室应变力之间的差异以及患者左心室射血分数与应变力参数之间的联系。结果:与对照组相比,DCM患者的GPRS、GPCS、GPLS远低于对照组[(7.22±3.03)%、(-5.51±2.33)%、(-3.71±2.11)%vs.(52.75±28.52)%、(-20.89±4.05)%、(-14.52±2.75)%,P<0.01]。GPCS与GPRS呈高度负相关(R=-0.867,P<0.01),EF与GPRS、GPCS分别呈中度相关(R=0.689,P<0.01;R=-0.619,P<0.01)、与GPLS呈轻度都负相关(R=-0.327,P<0.05);GPLS与GPRS、GPCS、EF分别呈轻度负相关(R=-0.472,P<0.01;R=0.471,P<0.01)。结论:磁共振心肌特征追踪成像不仅可以定量测量DCM患者心肌应变力,还可显示出心肌疾病的严重程度,在识别左室心肌功能障碍及评估疾病进展阶段方面有重大意义,也在一定程度上明确了应变力与心肌纤维走行之间的关系。
Objective:The aim of this study was to quantitatively evaluate the changes of left ventricular myocardial strain in patients with dilated cardiomyopathy(DCM)by magnetic resonance myocardial tissue tracking technique.Methods:60 patients with myocarditis diagnosed in our hospital in the past two years were collected continuously,and meanwhile 76 healthy adult volunteers were recruited as control group.The left ventricular global peak radial strain(GPRS),global peak long strain(GPLS),global peak circumferential strain(GPCS)and LV ejection fraction(LVEF)were measured,and then the changes of global left ventricular peak strain and LVEF between the two groups were investigated.Results:Compared with healthy adult volunteers,GPRS,GPCS,GPLS of patients with DCM was significantly lower[(7.22±3.03)%,(-5.51±2.33)%,(-3.71±2.11)%vs.(52.75±28.52)%,(-20.89±4.05)%,(-14.52±2.75)%,P<0.01].There was a significantly negative correlation between GPRS and GPCS(R=-0.867,P<0.01).LVEF was moderately correlated with GPRS and GPCS,respectively(R=0.689,P<0.01;R=-0.619,P<0.01);LVEF was lightly correlated with GPLS(R=-0.327,P<0.05).GPLS was lightly negatively correlated with GPRS,GPCS(R=-0.472,P<0.01;R=0.471,P<0.01).Conclusions:LV myocardial strain in patients with DCM can be quantitatively measured by myocardial feature tracking,which is of great significance in early identification of myocardial dysfunction and assessment of its progression,Also it clarifies the relationship between strain and myocardial fiber orientation to a certain extent.
作者
李舒曼
程敬亮
张勇
张文博
金红瑞
靳雅楠
LI Shu-man;CHEN Jing-liang;ZHANG Yong(Department of Magnetic Resonance,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)
出处
《放射学实践》
北大核心
2020年第11期1429-1433,共5页
Radiologic Practice
关键词
心脏磁共振成像
特征追踪
心肌病
扩张型
心肌应变力
Cardiac magnetic resonance imaging
Feature tracking
Cardiomyopathy,dilated
Myocardial strain
