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桃金娘油复方喷剂在学龄期儿童急性分泌性中耳炎的疗效观察 被引量:5

Clinical efficacy of myrtle oil compound spray on acute secretory otitis media in school-age children
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摘要 目的观察桃金娘油复方喷剂配合自动咽鼓管吹张仪在学龄期儿童急性分泌性中耳炎治疗中的临床疗效及安全性。方法选取2019月6月~2020年4月在浙江大学医学院附属杭州市第一人民医院接受治疗的急性分泌性中耳炎患者72例作为研究对象,数字随机分为实验组和对照组各36例,对照组给予抗生素结合自动咽鼓管吹张仪治疗,实验组在对照组基础上加用桃金娘油复方喷剂,统计治疗后2周、4周的疗效及声导抗鼓室图情况、有无并发症、复发率及不良反应等数据,并进行统计学分析。结果治疗2周后实验组治愈率、有效率高于对照组,差异具有统计学差异(t治愈率=8.000,t有效率=8.050,P均<0.05);治疗4周后实验组治愈率高于对照组,差异具有统计学差异(t=5.791,P<0.05);治疗4周后实验组有效率高于对照组,但差异无明显统计学意义(t=5.801,P>0.05);治疗2周后B型(平坦)及C型(负压)鼓室图实验组低于对照组,组间差异具有统计学意义(t=9.455,P<0.05);治疗4周后B型(平坦)及C型(负压)鼓室图实验组低于对照组,组间差异具有统计学意义(t=7.407,P<0.05)。两组患者随诊8周,期间未出现不良反应,无复发,安全性良好。结论学龄期儿童急性分泌性中耳炎实验组效果优于对照组,能缩短病程,安全性良好,值得临床推广。 OBJECTIVE To observe the clinical efficacy and safety of myrtle oil compound spray combined with autoinflation in the treatment of acute secretory otitis media in school-age children.METHODS 72 patients with acute secretory otitis media treated in our hospital from June 2019 to April 2020 were randomly divided into the experimental group and the control group,36 cases in each group.The control group was treated with antibiotics and autoinflation.The experimental group was added with myrtle oil compound spray on the basis of the control group,and the effect of 2 weeks and 4 weeks after treatment and the tympanogram change were statistically analyzed.There were no complications,recurrence and adverse reactions.RESULTS After 2 weeks of treatment,the cure rate and effective rate of the experimental group were higher than those of the control group,the difference was statistically significant(tcurerate=8.000,teffective rate=8.050,P all<0.05);after 4 weeks of treatment,the cure rate of the experimental group was higher than that of the control group,the difference was statistically significant(t=5.791,P<0.05).After 4 weeks of treatment,the effective rate of the experimental group was higher than that of the control group,but the difference was not statistically significant(t=5.801,P>0.05).After 2 weeks of treatment,B (flat) tympanogram and C(negative pressure) tympanogram in the experimental group were lower than those in the control group,and the difference between the two groups was statistically significant(t=9.455,P<0.05).After 4 weeks of treatment,B(flat) and C(negative pressure) tympanogram of the experimental group was lower than that of the control group,and the difference between the two groups was statistically significant(t=7.407,P<0.05).Two groups of patients were followed up for 8 weeks,no adverse reactions and recurrence were found.CONCLUSIONThe effect of the treatment group is better than that of the control group,which can shorten the course of the disease with good safety and is worthy of clinical promotion.
作者 楼响瑜 高月秋 曹晓林 管明 LOUXiangyu;GAO Yueqiu;CAO Xiaolin;GUAN Ming(Department of Otolaryngology,Hangzhou First People's Hospital,Zhejiang University School of Medicine,Hangzhou,Zhejiang,310006,China)
出处 《中国耳鼻咽喉头颈外科》 CSCD 2020年第10期568-571,共4页 Chinese Archives of Otolaryngology-Head and Neck Surgery
关键词 中耳炎 伴渗出液 儿童 临床方案 桃金娘油复方喷剂 Otitis Media with Effusion Child Clinical Protocols myrtle oil compound spray
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