摘要
目的探讨间断素食和限食对正常体重2型糖尿病患者糖脂代谢的影响。方法选择2017年8月—2019年6月本院内分泌科门诊就诊的48例2型糖尿病患者作为研究对象,随机分为素食组、限食组和对照组三组,每组各16例。素食组每周五日素食两日普食,限食组每周五日普食两日限食,对照组进行常规营养学治疗。所有患者于入组前及治疗16周后分别检测:FPG、2 hPG、HbA1c、BMI、SBP、DBP、TG、CHOL、HDL-C、LDL-C,并计算HOMA-IR。结果素食组和限食组治疗后的FPG、2 hPG、HbA1c、SBP、TG、CHOL、LDL-C、HOMA-IR均比对照组低,差异有统计学意义(P<0.05);素食组治疗后的CHOL、LDL-C比限食组低,差异有统计学意义(P<0.05);限食组治疗后的BMI比素食组和对照组低,差异有统计学意义(P<0.05)。结论间断素食和限食均能改善正常体重2型糖尿病患者的血糖、血压和血脂。间断限食模式有额外降低BMI的作用,间断素食则有额外降低CHOL和LDL-C的作用。两种饮食模式均值得临床推广。
Objective To explore the influence of intermittent vegetarian diet and food restriction on glucose and lipid metabolism in type 2 diabetes mellitus patients with normal body weight.Methods 48 patients with type 2 diabetes mellitus those treated in the outpatients department of our hospital from August 2017 to June 2019 were enrolled as study subjects and they were randomly divided into vegetarian group,food restriction group and control group,with 16 cases in each group.The vegetarian group received five-day vegetarian diet and two-day normal diet every week.The food restriction group received five-day normal diet and two-day limited diet every week.The control group received conventional diabetes nutrition treatment.Before they entered the study and 16 weeks after the treatment,concentrations of FPG,2hPG,HbA1c,BMI,SBP,DBP,TG,CHOL,HDL-C and LDL-C of all the patients were detected and calculated the HOMA-IR.Results After 16 weeks of treatment,the levels of FPG,2hPG,HbA1c,SBP,TG,CHOL,and LDL-C in the vegetarian group and food restriction group were lower than those in the control group(P<0.05).After the treatment,the levels of CHOL and LDL-C in the vegetarian group were lower than those in the food restriction group(P<0.05).The level of BMI in the food restriction group was lower than vegetarian group and control group(P<0.05).Conclusions The two dietary patterns of five-day vegetarian diet every week and two-day limited diet every week could improve blood glucose,blood pressure,and blood lipid level for type 2 diabetes mellitus patients with normal body weight.The two-day limited diet every week has additional effect of reducing BMI,and intermittent vegetarian diet has additional effect of reducing CHOL and LDL-C.Both methods are worthy of clinical application.
作者
陈翔
蔡吓明
李花英
孙晗
许军军
CHEN Xiang(Department of endocrinology,affiliated hospital of Putian University,Putian,Fujian,351100,China)
出处
《齐齐哈尔医学院学报》
2020年第17期2134-2137,共4页
Journal of Qiqihar Medical University
基金
莆田学院校内科研项目(2017053)。
关键词
间断素食
间断限食
2型糖尿病
Intermittent vegetarian diet
Intermittent diet restriction
Type 2 diabetes
