摘要
目的观察固肾益精汤及联合经皮椎体成形术(PVP)治疗骨质疏松性胸腰椎体压缩性骨折临床疗效及对患者功能障碍指数(Oswestry)的影响。方法将本院收治的骨质疏松性胸腰椎体压缩性骨折患者84例随机分为对照组及中药联合组各42例,对照组给予PVP治疗,中药联合组在对照组治疗基础上联合固肾益精汤治疗,对比两组患者治疗前及治疗6个月后Oswestry功能障碍指数及临床疗效,测定两组治疗前后各项骨代谢指标,统计6个月内二次骨折发生情况测定治疗前后患者手术椎体下-椎体骨密度并对比。结果治疗后中药联合组Oswestry功能障碍指数评分显著低于对照组(P<0.05);中药联合组临床总有效率显著高于对照组(P<0.05);治疗后多项骨代谢指标及骨密度均为中药联合组优于对照组(P<0.05);中药联合组二次骨折发生率显著低于对照组(P<0.05)。结论固肾益精汤联合PVP治疗骨质疏松性胸腰椎体压缩性骨折方案疗效确切,患者功能障碍改善效果明显,且可显著降低患者术后二次骨折发生率。
Objective To observe the clinical effect of Gushen Yijing Decoction combined with percutaneous vertebroplasty(PVP) in treatment of osteoporotic thoracolumbar compression fracture and its effect on Oswestry.Methods 84 cases of patients with osteoporotic thoracolumbar compression fracture were randomly divided into control group and traditional Chinese medicine(TCM) combined group,42 cases in each group.Control group was treated with PVP,and TCM combined group was treated with Gushen Yijing Decoction on the basis of control group.The Oswestry dysfunction index and clinical efficacy of the two groups were compared before and 6 months after treatment,and the bone metabolism indexes before and after the treatment were measured.The incidence of secondary fracture within 6 months was counted,and the BMD of the patients before and after operation was measured and compared.Results After treatment,Oswestry dysfunction index score of TCM combined group was significantly lower than that of control group(P<0.05);the total clinical effective rate of TCM combined group was significantly higher than that of control group(P<0.05);multiple bone metabolism indexes and bone density of TCM combined group were better than that of control group(P<0.05);the secondary fracture rate of TCM combined group was significantly lower than that of control group(P<0.05).Conclusion The treatment of osteoporotic thoracolumbar vertebral body compression fracture with Gushen Yijing Decoction and PVP has definite curative effect,obvious improvement effect of patients’ dysfunction,and can significantly reduce the incidence of secondary fracture after operation.
作者
陈小龙
辛坤
赵光辉
范吉众
刘旭
CHEN Xiaolong;XIN Kun;ZHAO Guanghui;FAN Jizhong;LIU Xu(The Second Department of Orthopaedics,Taihe Hospital of Traditional Chines)
出处
《湖北中医药大学学报》
2020年第4期94-96,共3页
Journal of Hubei University of Chinese Medicine
基金
安徽省卫生计生委中医药科研项目(项目编号:2014zy74)。
