摘要
放射性口腔黏膜炎(RTOM)是头颈部肿瘤患者放疗后常见的并发症,急性期表现为轻度红斑到深部黏膜溃疡不等,伴随的口腔局部疼痛影响精神、食欲,进而对全身状况产生不利影响,导致放疗中断,最终影响抗肿瘤治疗的效果。目前,针对RTOM主要进行预防和对症治疗。药物包括漱口液、口腔黏膜保护剂、口服药及雾化等,在预防及缓解口腔黏膜炎症状方面取得了良好效果。非药物治疗主要包括基础口腔护理、光生物调节疗法及抗菌光动力疗法。未来仍需进行更多的研究以制订RTOM标准化治疗模式。
Radiation-induced oral mucositis(RTOM)is the most common complication in patients with head and neck cancer after radiotherapy.The clinical manifestations in the acute stage range from mild erythema to deep mucosal ulcers.The accompanying oral pain affects the spirit and appetite,and then has adverse effects on the general condition,leading to the interruption of radiotherapy,and ultimately affecting the effect of anti-tumor treatment.At present,the preventive and symptomatic treatments of RTOM are the main countermeasures being carried out.Drugs including mouthwash,oral mucosal protective agent,oral medicine and atomization have achieved good results in preventing and relieving oral mucosal inflammation.Non-drug treatment mainly include basic oral care,photobiological therapy and antibacterial photodynamic therapy.More research is needed in the future to develop a standardized treatment model for RTOM.
作者
高燕
杨连平
GAO Yan;YANG Lianping(Shanxi Medical University Hospital of Stomatology,Taiyuan 030001,China;Department of Stomatology,the Second Hospital of Shanxi Medical University,Taiyuan 030001,China)
出处
《医学综述》
2020年第22期4494-4498,共5页
Medical Recapitulate
关键词
放射性口腔黏膜炎
口腔黏膜炎
口腔黏膜损伤
防治
头颈部癌
Rdiation-induced oral mucositis
Oral mucositis
Oral mucosal injury
Prevention and treatment
Head and neck cancer
