摘要
目的探讨白细胞计数、C反应蛋白与红细胞沉降率检测在儿童肺炎中的价值。方法选择2017年1月至2018年10月杭州市儿童医院就诊的肺炎患儿100例与行健康体检的健康儿童100例,分别设置为肺炎组、对照组。采集两组受检儿童的空腹静脉血,对血液中的白细胞计数、C反应蛋白、红细胞沉降率进行检测,比较肺炎组与对照组、轻症组与重症组、细菌性肺炎组与病毒性肺炎组的白细胞计数、C反应蛋白、红细胞沉降率。采用皮尔逊相关系数分析法,分析白细胞计数、C反应蛋白、红细胞沉降率与肺炎发生、病情严重程度、病因的相关性。结果(1)肺炎组的白细胞计数[(13.56±4.31)×10^9/L]、C反应蛋白[(10.27±4.82)mg/L]、红细胞沉降率[(17.63±5.78)mm/h]均高于对照组(t=10.308、9.012、10.088,均P<0.05)。(2)重症组的白细胞计数[(15.19±2.97)×10^9/L]、C反应蛋白[(11.79±3.14)mg/L]、红细胞沉降率[(19.24±3.20)mm/h]均高于轻症组(t=6.002、5.404、5.460,均P<0.05)。(3)细菌性肺炎组的白细胞计数[(15.31±3.34)×10^9/L]、C反应蛋白[(11.92±3.29)mg/L]、红细胞沉降率[(19.40±3.52)mm/h]均高于病毒性肺炎组(t=4.692、4.685、4.687,均P<0.05)。(4)经相关性分析,白细胞计数、C反应蛋白、红细胞沉降率与肺炎的发生、病情严重程度、病因均存在线性相关,呈正相关。结论肺炎患儿的白细胞计数、C反应蛋白、红细胞沉降率普遍出现异常增高,临床上可通过检测患儿的白细胞计数、C反应蛋白、红细胞沉降率来对肺炎予以辅助诊断,还可用于肺炎的病情评估、疗效判断中。
Objective To study the clinical value of white blood cell count,C-reactive protein(CRP)and erythrocyte sedimentation in children with pneumonia.Methods From January 2017 to October 2018,100 children with pneumonia and 100 healthy children who underwent physical examination in Hangzhou Children's Hospital were divided into two groups:pneumonia group and control group.The fasting venous blood was collected from the two groups.The white blood cell count,CRP and erythrocyte sedimentation were compared between the pneumonia group and the control group,the mild group and the severe group,bacterial pneumonia group and viral pneumonia group.Pearson correlation coefficient analysis was used to analyze the correlation between white blood cell count,CRP,erythrocyte sedimentation and the occurrence,severity and etiology of pneumonia.Results(1)White blood cell count[(13.56±4.31)×10^9/L],CRP[(10.27±4.82)mg/L]and erythrocyte sedimentation[(17.63±5.78)mm/h]in the pneumonia group were all higher than those in the control group(t=10.308,9.012,10.088,all P<0.05).(2)White blood cell count[(15.19±2.97)×10^9/L],CRP[(11.79±3.14)mg/L]and erythrocyte sedimentation[(19.24±3.20)mm/h]in the severe group were all higher than those in the mild group(t=6.002,5.404,5.460,all P<0.05).(3)The white blood cell count[(15.31±3.34)×10^9/L],CRP[(11.92±3.29)mg/L]and erythrocyte sedimentation[(19.40±3.52)mm/h]in the bacterial pneumonia group were higher than those in the viral pneumonia group(t=4.692,4.685,4.687,all P<0.05).(4)By correlation analysis,the white blood cell count,CRP,erythrocyte sedimentation were linearly correlated with the occurrence,severity and etiology of pneumonia.Conclusion The white blood cell count,CRP and erythrocyte sedimentation amount of children with pneumonia are abnormally increased.The clinical diagnosis of pneumonia can be aided by the detection of white blood cell count,CRP and erythrocyte sedimentation.It can also be used to evaluate the condition of pneumonia and to judge the curative effect.
作者
王云桥
Wang Yunqiao(Department of Clinical Laboratory,Hangzhou Children's Hospital,Hangzhou,Zhejiang 310014,China)
出处
《中国基层医药》
CAS
2020年第22期2694-2697,共4页
Chinese Journal of Primary Medicine and Pharmacy
基金
浙江省医学会临床科研项目(2013ZYC-A46)。
关键词
儿童
肺炎
细菌性
病毒性
白细胞计数
C反应蛋白
红细胞沉降率
Children
Pneumonia
Bacterial
Virus
Leukocyte count
C-reactive protein
Erythrocyte sedimentation
