摘要
目的探讨妊娠期糖尿病孕妇医学营养干预方法和效果,及对母婴妊娠结局的影响。方法选取2018年1月至2019年1月接受治疗的160例妊娠期糖尿病患者为研究对象,将其随机分为对照组和观察组,各80例。对照组给予常规产检+适当运动指导,观察组在对照组基础上采用医学营养干预,对比分析两组患者的血糖水平[空腹血糖(FPG)、餐后2h血糖(2hPG)]、糖化血红蛋白(HbA1c)以及母婴结局。结果干预后,观察组FPG、2hPG和HbA1c水平均低于干预前,且观察组低于对照组,差异有统计学意义(P<0.01)。观察组妊娠期高血压(15.00%vs 3.75%,P<0.05)、羊水过多(18.75%vs 2.50%,P<0.01)、巨大儿发生率(17.50%vs 5.00%,P<0.05)低于对照组,差异有统计学意义。结论对妊娠期糖尿病孕妇给予医学营养干预,可有效控制血糖水平,并显著降低母婴不良妊娠结局。
Objective To explore the method and effect of medical nutrition intervention for pregnant women with gestational diabetes mellitus(GDM)and its influences on the outcome of pregnancy so as to provide reference for clinical treatment.Methods A total of 160 GDM patients treated from January 2018 to January 2019 were randomly divided into control group and observation group(n=80,each).Based on the conventional pregnancy check-up and proper exercise guidance in two groups,medical nutrition intervention was given in observation group.The blood glucose and glycosylated hemoglobin(HbA1c)levels and maternal and infant outcomes were compared between two groups.Results Before intervention,there were no statistical differences in FPG,2hPG and HbA1c between two groups(P>0.05).After intervention,the levels of FPG,2hPG and HbA1c significantly decreased compared with those before intervention in both groups and were statistically lower in observation group than those in control group(P<0.01).The incidence of pregnancy hypertension,excessive amount of amniotic fluid and macrosomia in observation group were significantly lower than those in control group(P<0.05,P<0.01),and there was no statistical difference in the incidence of preterm birth and neonatal asphyxia between two groups(P>0.05).Conclusion For pregnant women with GDM,medical nutrition intervention can control blood glucose level effectively and reduce adverse pregnancy outcome for both mother and infant obviously.
作者
张春兰
王灿
ZHANG Chun-lan;WANG Can(Department of Obstetrics and Gynecology,the First People's Hospital of Chuzhou,Chuzhou,Anhui 239000,China)
出处
《中国临床研究》
CAS
2020年第11期1527-1529,共3页
Chinese Journal of Clinical Research
关键词
妊娠期糖尿病
医学营养干预
空腹血糖
口服葡萄糖耐量试验
糖化血红蛋白
妊娠结局
Gestational diabetes mellitus
Medical nutrition intervention
Fasting blood glucose
Oral glucose tolerance test
Glycosylated hemoglobin
Pregnancy outcome
