摘要
中华卷柏为卷柏科卷柏属植物,卷柏属共有700余种植物,其中中华卷柏为中国特有。中华卷柏的传统药用功效主要包括清热利湿、止血化痰等。现代研究发现,中华卷柏还表现出多种药理活性,并在抗炎、抗肿瘤及抗氧化等方面具有良好的临床效果。其化学成分主要有黄酮、木脂素以及糖苷等,其中双黄酮类成分是近年来的研究热点之一,具有很好的研究价值和应用前景。本文对中华卷柏的生药学、化学成分及药理活性等研究进展进行综述,为中华卷柏的药效物质基础以及活性成分的开发和利用提供更多的科学依据。
Selaginella sinensis(Desv.)Spring belongs to the genus Selaginella of the Selaginellaceae family.There are more than 700 species of plants in the Selaginella genus,of which S.sinensis is endemic to China.The traditional medicinal efficacy of S.si⁃nensis includes clearing heat and dampness,stopping bleeding and reducing phlegm,etc.Modern studies have shown that S.sinensis also exhibits a variety of pharmacological activities and has good therapeutic effects in the clinical application for the anti-inflammato⁃ry,anti-tumor and anti-oxidation purposes.Its chemical components are mainly flavonoids,lignans,and glycosides.Among them,bis⁃flavonoids have become one of the research hotspots in recent years,and showed valuable research and promising application pros⁃pects.This paper reviews the research progress in pharmacognosy,chemical constituents and pharmacological activities of S.sinensis,so as to provide reference for further research and development of S.sinensis.
作者
郑鑫
温静
李文兰
阎新佳
刘畅
江园园
ZHENG Xin;WEN Jing;LI Wen-lan;YAN Xin-jia;LIU Chang;JIANG Yuan-yuan(Heilongjiang Provincial Key Laboratory of Drug Prevention and Treatment for Senile Diseases,College of Pharmacy,Harbin University of Commerce,Harbin 150076,China)
出处
《国际药学研究杂志》
CAS
北大核心
2020年第9期698-702,708,共6页
Journal of International Pharmaceutical Research
基金
黑龙江省普通本科高等学校青年创新人才培养计划(UNPYSCT-2017201)。
关键词
中华卷柏
化学成分
药理活性
生药学
研究进展
Selaginella sinensis(Desv.)Spring
chemical constituents
pharmacological activity
pharmacognosy
research progress
