摘要
目的:研究脊髓型颈椎病患者血脂水平与颈椎间盘退变的相关性。方法:收集弋矶山医院骨科44名脊髓型颈椎病患者年龄、高血压史等一般信息,男性18例,女性26例,并收集12例颈部脊髓损伤患者作为对照组。收集患者住院期间所做MRI检查以及空腹血脂参数,根据改良的Pfirmann椎间盘退变分级对患者的致病椎间盘进行评分和记录。结果:脊髓型颈椎病患者年龄和颈椎退变呈正相关(P<0.05)。在患者血脂参数与椎间盘退变的分析中,患者总胆固醇(GHOL)、甘油三脂(TG)水平与患者椎间盘退变呈正相关(P<0.05),而低密度脂蛋白(LDL)、高密度脂蛋白(HDL)与椎间盘退变相关性无统计学意义(P>0.05)。结论:高龄、高甘油三酯和高总胆固醇能够加重椎间盘退变,是引起颈椎病的危险因素。
Objective:To investigate the correlation between blood lipid levels and cervical disc degeneration in patients with cervical spondylotic myelopathy.Methods:Forty-four patients(18 males and 26 females)with cervical spondylotic myelopathy treated in our department were included,and theiRgeneral information,such as the patient′s age and history of hypertension,was collected.Another 12 patients with cervical spinal cord injury were recruited as controls.The MRI and fasting lipid parameters of the patients during hospitalization were also obtained.The diseased discs were scored in patients and measured according to the modified Pfirmann grading system.Results:The age of patients with cervical spondylotic myelopathy was positively correlated with cervical degeneration(P<0.05).Analysis of the patient′s blood lipid indicators and intervertebral disc degeneration demonstrated that the patient′s total cholesterol(GHOL)and triglyceride(TG)levels were positively correlated with the patient′s intervertebral disc degeneration(P<0.05),yet low density lipoprotein(LDL)and high density(HDL)were not statistically associated with intervertebral disc degeneration(P>0.05).Conclusion:Old age,high triglycerides and high total cholesterol are risk factors for cervical spondylosis,and can aggravate intervertebral disc degeneration.
作者
詹文豪
王弘
王凌挺
白凡
朱孝峰
齐美涛
ZHAN Wenhao;WANG Hong;WANG Lingting;BAI Fan;ZHU Xiaofeng;QI Meitao(Department of Spinal Surgery,The First Affiliated Hospital of Wannan Medical College,Wuhu 241001,China)
出处
《皖南医学院学报》
CAS
2020年第6期531-533,共3页
Journal of Wannan Medical College
基金
芜湖市科技计划项目(2019rkx4-2)。
关键词
血脂
脊髓型颈椎病
椎间盘退变
blood lipid
cervical spondylotic myelopathy
intervertebral disc degeneration
