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美罗培南静脉注射联合布地奈德雾化吸入在呼吸机相关性肺炎中的治疗效果研究 被引量:1

Effect of intravenous injection of Meropenem combined with atomization inhalation of Budesonide in the treatment of ventilator-associated pneumonia
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摘要 目的:探讨美罗培南静脉注射联合雾化吸入治疗呼吸机相关性肺炎的疗效。方法:2018年2月-2020年2月收治呼吸机相关性肺炎患者86例,随机分为研究组和对照组各43例。对照组给予美罗培南治疗;研究组给予美罗培南静脉注射联合布地奈德雾化吸入治疗。观察分析两组临床疗效、血液指标变化情况以及不良反应发生率等。结果:研究组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。研究组治疗总有效率明显高于对照组,差异有统计学意义(P<0.05)。研究组患者WBC计数明显低于对照组,PaO2水平明显高于对照组,差异有统计学意义(P<0.05)。结论:呼吸机相关性肺炎患者应用美罗培南静脉注射联合布地奈德雾化吸入治疗能发挥出比较理想的作用,能有效增强治疗效果,减少不良反应发生率,促进患者各项血液指标改善,其用药安全性以及可靠性均相对较高,可推广使用。 Objective:To observe the efficacy of meropenem intravenous injection combined with aerosol inhalation in the treatment of ventilator-associated pneumonia.Methods:From February 2018 to February 2020,86 patients were randomly divided into study group and control group with 43 cases each.The control group was given meropenem treatment.The study group was given intravenous injection of Meropenem and inhalation of budesonide.To observe and analyze the therapeutic effect,blood index changes and the incidence rate of adverse reactions in the two groups.We compared the therapeutic effects of the two groups.Results:The incidence of adverse reactions in the study group was lower than that in the control group,the difference was statistically significant(P<0.05).The total effective rate of the study group was significantly higher than that of the control group,the difference was statistically significant(P<0.05).In the study group,the WBC count of the patients was significantly lower than that of the control group,and the PaO2 level was significantly higher than that of the control group,the difference was statistically significant(P<0.05).Conclusion:patients with ventilator associated pneumonia application beauty e.faecalis intravenous injection with budesonide atomization inhalation therapy may play a role of the ideal,can effectively enhance the treatment effect,reduce the rate of adverse reaction,improve patients the blood indexes,the medication safety and reliability are relatively high,can promote the use.
作者 庞春 Pang Chun(The People's Hospital of Siyang County,Jiangsu Suqian 223700)
机构地区 泗阳县人民医院
出处 《中国社区医师》 2020年第34期20-21,共2页 Chinese Community Doctors
关键词 美罗培南静脉注射 布地奈德雾化吸入治疗 呼吸机相关性肺炎 Meropenem intravenous injection Inhalation of budesonide Ventilator-associated pneumonia
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