摘要
目的探讨调强放射治疗对鼻咽癌患者口腔黏膜及免疫功能的影响。方法选择辽宁省抚顺市第四医院50例2014年2月至2015年7月鼻咽癌患者。随机分组,二维放射治疗组患者采取二维放射方案治疗,调强放射治疗组患者则采取调强放射治疗。比较效果。结果调强放射治疗组治疗总有效率高于二维放射治疗组,P<0.05。治疗后调强放射治疗组免疫功能指标淋巴细胞白细胞分化抗原8^+、淋巴细胞白细胞分化抗原4^+、淋巴细胞白细胞分化抗原4^+/淋巴细胞白细胞分化抗原8^+、生存总时间、口腔黏膜急性反应发生率明显优于二维放射治疗组,P<0.05。结论调强放射治疗鼻咽癌可获得较好预后。
Objective To investigate the effect of intensity modulated radiation therapy on oral mucosa and immune function in patients with nasopharyngeal carcinoma.Methods Fifty patients with nasopharyngeal carcinoma from February 2014 to July 2015 were selected from the Fourth Hospital of Fushun City,Liaoning Province.Randomly grouped,patients in the two-dimensional radiotherapy group were treated with two-dimensional radiotherapy,and patients in the intensity-modulated radiotherapy group were treated with intensity-modulated radiation.Compare the effect.Results The intensity-modulated radiotherapy group had a higher total effective rate of treatment,P<0.05.After treatment,the immune function indicators of lymphocyte differentiation antigen 8^+,lymphocyte leukocyte differentiation antigen 4^+,lymphocyte leukocyte differentiation antigen 4^+/lymphocyte leukocyte differentiation antigen 8^+were more variable after treatment,P<0.05.The total survival time of the intensity-modulated radiotherapy group was better,P<0.05.The incidence of acute mucosal acute reaction in the intensity-modulated radiotherapy group was lower than that in the two-dimensional radiotherapy group(P<0.05).Conclusion Intensive radiation therapy for nasopharyngeal carcinoma can obtain a better prognosis.
作者
安红祥
AN Hongxiang(The Fourth Hospital of Fushun City,Liaoning Province,Fushun 113006,China)
出处
《中国医药指南》
2020年第31期98-99,共2页
Guide of China Medicine
关键词
鼻咽癌
调强放射治疗
口腔黏膜
免疫功能
影响
Patients with nasopharyngeal carcinoma
Intensity-modulated radiation therapy
Oral mucosa
Immune function
Influence
