摘要
目的探讨氦氖激光联合中药熏洗治疗外阴鳞状上皮增生的价值。方法选择江西省上饶市妇幼保健院2017年2月~2019年2月收治的80例外阴鳞状上皮增生患者,根据随机数字表法分组原则将其分为观察组(n=40)和对照组(n=40)。对照组给予氦氖激光治疗,在对照组基础上,观察组加用中药熏洗治疗,连续治疗1个月,比较两组临床疗效、临床症状评分、复发情况及不良反应发生情况。结果观察组总有效率高于对照组,差异有统计学意义(P<0.05)。治疗1个月后,两组瘙痒、干燥、脱屑评分均低于治疗前,且观察组评分低于对照组,差异均有统计学意义(P<0.05)。观察组患者随访1年内的总复发率低于对照组,差异有统计学意义(P<0.05)。治疗期间未发现有与药物相关的过敏反应及其他不良反应。结论氦氖激光联合中药熏洗可改善外阴鳞状上皮增生患者的临床症状,降低复发率,且安全性较高,值得临床推广应用。
Objective To explore the value of He-Ne laser combined with Chinese medicine fumigation in the treatment of vulvar squamous epithelial hyperplasia.Methods A total of 80 patients with vulval squamous epithelial hyperplasia admitted to Shangrao Maternal and Child Health Hospital from February 2017 to February 2019 were selected and divided into observation group(n=40)and control group(n=40)according to the principle of random number table method.The patients in control group were treated with He-Ne laser.On the basis of the control group,the patients in observation group were treated with fumigation and washed with traditional Chinese medicine.Clinical efficacy,clinical symptom score,recurrence and adverse event incidence were compared between the two groups.Results The total clinical effective rate in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).Pruritus,dryness and desquamation scores of patients in the observation group after 1 month of treatment were all lower than those in the control group,with statistically significant differences(P<0.05).The total recurrence rate of the observation group after 1 year follow-up was lower than that of the control group,and the difference was statistically significant(P<0.05).No drug-related allergic reactions or other adverse reactions were found during the treatment.Conclusion He-Ne laser combined with traditional Chinese medicine fumigation can improve the clinical symptoms of patients with vulvar squamous epithelial hyperplasia,reduce the recurrence rate,and has high safety,which is worthy of clinical application.
作者
钱丹
姜芳燕
吴鲜花
黄玲
何舰
QIAN Dan;JIANG Fang-yan;WU Xian-hua;HUANG Ling;HE Jian(Department of Diagnosis and Treatment of Cervical Diseases,Shangrao Maternal and Child Health Hospital,Jiangxi Province,Shangrao334000,China)
出处
《中国当代医药》
2020年第34期175-178,共4页
China Modern Medicine
基金
江西省卫生健康委科技计划项目(20204810)。
关键词
外阴鳞状上皮增生
氦氖激光
中药熏洗
临床疗效
临床症状评定
复发情况
不良反应发生率
Vulvar squamous epithelial hyperplasia
He-Ne laser
Chinese medicine fumigation and washing
Clinical efficacy
Evaluation of clinical symptoms
Recurrence
Incidence of adverse events
