摘要
目的分析登革热患者急性发热期与恢复期实验室指标的动态变化,为该病的早期诊断、治疗及预后评估提供数据支持。方法选取2019年1-12月该院收治的登革热患者65例作为研究对象,检测患者在急性发热期、恢复期的白细胞计数(WBC)、血小板计数(PLT)、血细胞比容(HCT)、淋巴细胞百分比(LYM%)、中性粒细胞百分比(NEUT%)、丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、肌酸激酶(CK)、肌酸激酶同工酶(CK-MB)水平,对检测结果及异常结果所占比例进行比较、分析。结果与急性发热期比较,登革热患者恢复期WBC、PLT水平升高,HCT、NEUT%水平降低,差异有统计学意义(P<0.05);登革热患者恢复期WBC、PLT、LYM%异常结果所占比例低于急性发热期,差异有统计学意义(P<0.05)。与急性发热期比较,登革热患者恢复期ALT、AST、CK、CK-MB水平明显降低,差异有统计学意义(P<0.05);登革热患者恢复期CK、CK-MB异常结果所占比例低于急性发热期,差异有统计学意义(P<0.05)。结论登革热患者存在部分血常规指标异常、肝损伤及心肌损伤,且急性发热期的损伤较为严重,在恢复期时有所改善。
Objective To analyze the dynamic changes of laboratory indexes in patients with dengue fever during acute fever period and recovery period,to provide data support for the early diagnosis,treatment and prognosis evaluation of the disease.Methods A total of 65 cases of dengue fever patients admitted to the hospital from January to December 2019 were selected as the research objects.Detected the patient's white blood cell count(WBC),platelet count(PLT),hematocrit(HCT),lymphocyte percentage(LYM%),neutrophil percentage(NEUT%),alanine aminotransferase(ALT),aspartate aminotransferase(AST),creatine kinase(CK)and creatine kinase isoenzyme(CK-MB)levels during acute fever period and recovery period.Compared and analyzed the detect results and the proportions of abnormal results.Results Compared with the acute fever period,the WBC and PLT levels in the recovery period of the dengue fever patients increased,and the HCT and NEUT%levels decreased,the differences were statistically significant(P<0.05).The proportion of abnormal results of WBC,PLT and LYM%in the recovery period of dengue fever patients were lower than those in the acute fever period,and the differences were statistically significant(P<0.05).Compared with the acute fever period,the ALT,AST,CK and CK-MB levels in the recovery period of the dengue fever patients were significantly decreased,and the differences were statistically significant(P<0.05).The proportion of abnormal results of CK and CK-MB in the recovery period of dengue fever patients were lower than those in the acute fever period,and the differences were statistically significant(P<0.05).Conclusion Patients with dengue fever have some abnormal blood routine indexes,liver damage and myocardial damage,and the damage in the acute fever period is more serious,and it improves in the recovery period.
作者
梁乐光
张七二
卢慧兵
LIANG Leguang;ZHANG Qi'er;LU Huibing(Department of Clinical Laboratory,Liaobu Hospital of Dongguan City,Dongguan,Guangdong 523000,China)
出处
《检验医学与临床》
CAS
2020年第24期3608-3610,3614,共4页
Laboratory Medicine and Clinic
关键词
登革热
急性发热期
恢复期
血常规
肝功能
心肌酶
dengue fever
acute fever period
recovery period
blood routine
liver function
myocardial enzymes
