摘要
目的观察针刺配合口服小青龙汤治疗小儿支气管肺炎的临床疗效。方法将128例小儿支气管肺炎患者随机分为治疗组和对照组,每组64例。对照组采用常规药物治疗,治疗组在对照组基础上采用针刺配合口服小青龙汤治疗。观察两组治疗前后各项影像学指标(肺纹理增粗、肺野斑片状阴影、肺门阴影增大或增浓、结构模糊或紊乱)、炎症因子指标[分泌型白细胞蛋白酶抑制因子(SLPI)、降钙素原(PCT)、肿瘤坏死因子-α(TNF-α)、超敏C反应蛋白(hs-CRP)、白细胞介素-6(IL-6)、可溶性细胞间黏附分子-1(sICAM-1)、几丁质酶-3样蛋白-1(YKL-40)]、肺功能指标[潮气量(VT)、吸气时间(TI)、呼气时间(TE)、吸呼比(TI/TE)、达峰时间比(TPF%TE)、达峰容积比(VPF%VE)]、症状(咯痰、咳嗽、肺部啰音、气促、紫绀、鼻塞流涕)评分及消失时间的变化情况。结果两组治疗后各项影像学指标、炎症因子指标、肺功能指标、症状评分及消失时间与同组治疗前比较差异均具有统计学意义(P<0.05)。治疗组治疗后各项影像学指标、炎症因子指标、肺功能指标、症状评分及消失时间与对照组比较差异均具有统计学意义(P<0.05)。结论针刺配合口服小青龙汤是一种治疗小儿支气管肺炎的有效方法。
Objective To observe the clinical efficacy of acupuncture plus oral administration of Xiao Qing Long decoction in treating bronchopneumonia in children.Method A total of 128 kids with bronchopneumonia were randomized into a treatment group and a control group,with 64 cases in each group.The control group was intervened by conventional medications,while the treatment group was given acupuncture plus oral administration of Xiao Qing Long decoction on the basis of the control group.Before and after treatment,the radiographic indexes(pulmonary texture thickening,patchy shadows in pulmonary pathogenic fields,expanded or thickened hilar shadow,and structure blurring or disorder),inflammatory factor indexes[secretory leukocyte peptidase inhibitor(SLPI),high-sensitivity C-reactive protein(hs-CRP),interleukin(IL)-6,soluble intercellular adhesion molecule-1(sICAM-1)and chitinase-3-like protein 1(YKL-40)],pulmonary function parameters[tidal volume(VT),time of inhalation(TI),time of exhalation(TE),ratio of inhalation to exhalation(TI/TE),ratio of time to peak tidal expiratory flow to total expiratory time(TPF%TE)and ratio of volume at peak tidal expiratory flow to expiratory tidal volume(VPF%VE)],symptom scores(expectoration,cough,lung rales,shortness of breath,cyanosis,nasal obstruction and runny nose)and the disappearing time of the symptoms were observed in each group.Result The radiographic findings,inflammatory factor indexes,pulmonary function parameters,symptom scores and the disappearing time of the symptoms changed significantly after treatment in both groups(P<0.05).After intervention,the radiographic findings,inflammatory factor indexes,pulmonary function parameters,symptoms scores and the disappearing time of the symptoms in the treatment group were significantly different from those in the control group(P<0.05).Conclusion Acupuncture plus oral administration of Xiao Qing Long decoction is an effective method in treating bronchopneumonia in children.
作者
程建虎
姜勇超
王伟
CHENG Jian-hu;JIANG Yong-chao;WANG Wei(Xiangyang Central Hospital,Xiangyang 441000,China)
出处
《上海针灸杂志》
2020年第12期1552-1557,共6页
Shanghai Journal of Acupuncture and Moxibustion
基金
湖北省卫生厅基金项目(WJ2015MB122)。
关键词
针刺疗法
支气管肺炎
小青龙汤
针药并用
炎症因子
肺功能
Acupuncture therapy
Bronchopneumonia
Xiao Qing Long decoction
Acupuncture medication combined
Inflammatory factors
Pulmonary function
