摘要
恶性腹膜间皮瘤是一种临床罕见,与石棉暴露密切相关的高侵袭性肿瘤。由于前期石棉材料的广泛应用,目前发病率呈明显上升趋势。该病起病隐匿,临床确诊时多为晚期,预后较差,中位生存期仅为12月。恶性腹膜间皮瘤治疗方法主要是肿瘤细胞减灭术联合腹腔热灌注化疗,目前多项免疫及分子靶向治疗正在研究中。本文就恶性腹膜间皮瘤的诊治现状作一综述,以期提高对该病的认识,进而为恶性腹膜间皮瘤的诊治提供参考。
Malignant peritoneal mesothelioma(MPM)is a rare and aggressive tumor and highly associated with asbestos exposure.Due to the wide application of asbestos materials in the early stage,the incidence of MPM is increasing now.The symptoms of MPM are atypical,so most of patients are in the late stage when diagnosed.And the prognosis is so poor that the median survival time is only 12 months.Now the main treatment of MPM is CRS-HIPEC,at the same time,a number of immune and targeted treatments are under study.This article reviews the current status of treatment on MPM,aiming to improve the understandings of this disease and provide a reference for the clinical diagnosis and treatment.
作者
李娜
陈忠坚
毛伟敏
LI Na;CHEN Zhongjian;MAO Weimin(Institute of Basic Medicine and Cancer(IBMC),Chinese Academy of Sciences,The Cancer Hospital of the University of Chinese Academy of Sciences(Zhengjiang Cancer Hospital),Hangzhou 310022,China)
出处
《肿瘤防治研究》
CAS
CSCD
2020年第12期992-995,共4页
Cancer Research on Prevention and Treatment
基金
国家自然科学基金(81672315)。
关键词
恶性腹膜间皮瘤
诊断
治疗
Malignant peritoneal mesothelioma
Diagnosis
Therapy
