摘要
目的探究孕期乙肝病毒感染对胎儿超声诊断影响,旨在为临床评估及防治孕期乙肝病毒感染提供依据。方法选取于2017年2月—2018年10月期间南阳市第二人民医院收治的82例孕期乙肝病毒感染患者,作为感染组,选取相同期内收治的80例孕期乙肝病毒携带患者,作为携带组,另选取在健康体检的82例肝功能正常未合并乙型肝炎病毒感染者孕妇作为对照组。针对所有的受试者采用Aplio500彩色多普勒超声诊断仪进行产前检查。观察比较感染组、携带组和对照组患者的分娩方式、围生期结局、母婴感染和胎盘体积、肝脏结构变化、妊娠期并发症等数据。结果(1)剖宫产率:感染组为34例(占41.46%),略高于携带组及对照组(P>0.05);(2)新生儿窒息率:感染组为16例(占19.51%),高于携带组及对照组(P<0.05)。(3)低体质量胎儿率:感染组为16例(占19.51%),高于携带组及对照组(P<0.05);(4)早产率:感染组为18例(占21.95%),高于携带组及对照组(P<0.05);(5)感染组患者的胎盘体积小于对照组(P<0.05);感染组患者的母婴传播率高于对照组(P<0.05),感染组的胎膜早破率、胎儿窘迫率高于携带组和对照组(P<0.05);(6)乙型肝炎病毒感染肝功能对照组、感染组、携带组胎儿,超声影像学检查均未探及肝脏结构有损害。结论妊娠期乙型肝炎病毒感染影响胎盘体积及围生期结局,增加患者妊娠期并发症,不利于母婴健康与安全。
Objective To explore the influence of HBV infection during pregnancy on fetal ultrasound diagnosis,in order to provide basis for clinical evaluation and prevention of HBV infection during pregnancy.Methods From February 2017 to October 2018,82 pregnant women with HBV infection in the hospital from Feb.2017 to Oct.2018 were selected as the infection group.80 pregnant women with HBV infection in the same period were selected as the carrier group,and 82 pregnant women with normal liver function and without HBV infection in the hospital were selected as the control group. All the subjects were examined with theAplio500 color Doppler ultrasound, and the delivery mode, perinatal outcome, mother infant infection, placental volume, liver struc⁃ture changes, pregnancy complications and other data of the patients in the infection group. The carrier group and the healthy con⁃trol group were compared. Results (1) Cesarean birth rate of 34 cases in the infection group (41.46%) was slightly higher thanthe carrying group and the control group (P>0.05). (2) neonatal asphyxia rate of 16 cases in the infection group (19.51%) washigher than Carrying group and control group (P<0.05). (3) Fetal rate of low body mass of 16 cases in the infection group (ac⁃counting for 19.51%) was higher than the carrier group and the control group (P<0.05). (4) Premature birth rate of 18 cases inthe infection group (accounting for 21.95%) was higher than the carrier group and control group (P<0.05). (5) Placenta volume ofpatients in infected group was smaller than that of control group (P<0.05);mother-to-child transmission rate of patients in infectedgroup was higher than that of control group (P<0.05). Premature rupture of membranes fetal distress rate in infection group were high⁃er than those in the carrier group and the control group (P<0.05). (6) The fetuses in the carrier group were not detected by ultra⁃sound imaging and the liver structure was damaged in three groups. Conclusion Hepatitis B virus infection in pregnancy affects pla⁃centa volume and perinatal outcome, increases pregnancy complications, and is not conducive to maternal and infant health and safety.
作者
刘小丽
LIU Xiao-li(The First Obstetrics,Nanyang Second People’s Hospital,Nanyang,Henan,473000,China)
出处
《黑龙江医学》
2020年第12期1690-1693,共4页
Heilongjiang Medical Journal
关键词
孕期
乙肝病毒
感染
胎儿
超声诊断
Pregnancy
Hepatitis B virus
Infection
Fetus
Ultrasound diagnosis
