摘要
目的通过调整用药剂量、采集间隔时间、采集速度等因素达到合理的放射性计数、骨与软组织计数的比值(T/NT),提高工作效率的同时达到图像质量的最优化。方法选取2020年6月中下旬在我科行SPECT全身骨显像患者,注射药物时随机分为A1、A2、A3三组,A1组注射药物555.8-740 MBq(15.1-20 mCi),A2组注射药物743.7-925 MBq(20.1-25)mCi,A3组注射药物928.1-1110 MBq(25.1-30 mCi);采集图像间隔时间随机分为B1、B2、B3三组,B1组注射药物后<2.5小时采集图像,B2组注射药物后2.5-3.5小时采集图像,B3组注射药物后>3.5小时采集图像;采集图像时随机分为C1、C2、C3三组,C1组采集速度为16 cm/min,C2组采集速度为20 cm/min,C3组采集速度为24 cm/min。根据全身骨显像前后位采集总计数将图像分为D1组(<2000 K)、D2组(2000 K-2500 K)和D3组(>2500 K)。勾画后位相胸10椎体与肋缘下软组织放射性计数,求出靶与非靶比值(T/NT),分为E1(T/NT<5)、E2(T/NT 5-10)、E3(T/NT>10)三组。显像完成后由两位中级以上核医学医师独立对图像质量进行评价,根据图像视觉观察清晰度、骨与软组织对比度分为优秀组、良好组、较差组。结果191例患者较差组38(20.0%);良好组78(40.8%)和优秀组75(39.2%)。结论SPECT全身骨图像质量与放射性总计数及骨与软组织比值(T/NT)关系密切。可通过调整注射药物剂量、采集间隔时间及采集速度获得合理的放射性总计数及骨与软组织比值,从而保证图像质量最优化。
Objective To achieve a reasonable radioactivity count and ratio of bone to soft tissue count (T/NT) by adjusting thedosage, collection interval and collection speed, so as to improve work efficiency and optimize image quality. Methods Patientswho underwent SPECT whole body bone imaging in our department in the middle and late June of 2020 were randomly dividedinto three groups: A1 group injected with 555.8-740MBq(15.1-20 mCi),A2 group injected with 743.7-925 MBq (20.1-25 mCi), andA3 group injected with 928.1-1110 MBq(25.1-30 mCi). The time interval of collecting images was randomly divided into threegroups: B1, B2 and B3. The images were collected less than 2.5 hours after drug injection in group B1, 2.5-3.5 hours after druginjection in group B2 and more than 3.5 hours after drug injection in group B3. Images were randomly divided into three groups:C1, C2 and C3. The acquisition speed of C1 group was 16cm/min, C2 group was 20 cm/min and C3 group was 24cm/min. Imageswere divided into D1 group (< 2000 K), D2 group (2000 K-2500 K) and D3 group (>2500 K) according to the total collection countof whole body bone imaging. The radioactivity counts of 10 thoracic vertebrae and soft tissues under costal margin in posteriorphase were sketched, and the ratio of target to non-target (T/NT) was calculated, which was divided into three groups: E1(T/NT<5),E2(T/NT 5-10) and E3(T/NT>10). After the completion of imaging, the image quality was evaluated independently by two nuclearmedicine doctors above intermediate level, and was divided into excellent group, good group and poor group according to the visualobservation clarity of the image and the contrast between bone and soft tissue. Results Among 191 patients, 38 (20.0%) were inpoor group. Good group 78(40.8%) and excellent group 75(39.2%). Conclusion The whole body bone image quality ofc SPECTis closely related to the total radioactivity count and the ratio of bone to soft tissue (T/NT). Reasonable total radioactivity countand bone/soft tissue ratio can be obtained by adjusting the injection dose, collection interval and collection speed, thus ensuring theoptimization of image quality.
作者
艾慧芳
李燕
蒲迪
张传栋
张君香
贾存玮
AI Huifang;LI Yan;PU Di;ZHANG Chuandong;ZHANG Junxiang;JIA Cunwei(Department of Medical Imaging,Affiliated Hospital of Jining Medical University,Jining Shandong 272029,China)
出处
《中国医疗设备》
2020年第S02期100-102,106,共4页
China Medical Devices
关键词
全身骨显像
图像质量
采集速度
放射性计数
whole body bone imaging
image quality
acquisition speed
radioactive counting
