摘要
BACKGROUND Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is a new virus responsible for the outbreak of respiratory illness known as coronavirus disease 2019(CoVID-19).Mycoplasma is an uncommon co-infected pathogen with SARSCoV-2 and has not yet been reported.Computed tomography(CT),used as an accessory examination,may play a more significant role in this co-infection.CASE SUMMARY A 49-year-old female presented with a cough,expectoration and chest congestion followed by elevated C-reactive protein and erythrocyte sedimentation rate.CT images showed ground-glass opacities in bilateral lower lobes and a patchy and striate shadow in the right upper lobe.Immunoglobulin M antibody of Mycoplasma pneumoniae was positive and real-time fluorescence polymerase chain reaction of sputum was positive for SARS-CoV-2 nucleic acid.The diagnosis of CoVID-19 was made based on laboratory results,chest CT images,clinical manifestations and epidemiologic characteristics.She was treated with combination therapy for 17 d and showed a marked reCoVery.CONCLUSION Co-infection with SARS-CoV-2 and Mycoplasma in CoVID-19 patients appears to be uncommon.CT is an acceptable method for the primary diagnosis and treatment should be initiated as soon as possible.Combination therapy with antiviral,anti-inflammatory,traditional Chinese herbal medicine and interferon inhalation may be a reference for further progress in treating this co-infection.