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经鼻持续呼吸道正压通气治疗新生儿窒息对气管插管率及并发症发生率的影响 被引量:2

The effect of nasal continuous positive airway pressure on the rate of intubation and complications in neonatal asphyxia
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摘要 目的研究经鼻持续呼吸道正压通气治疗新生儿窒息对气管插管率及并发症发生率的影响。方法纳入2018年8月~2019年8月收治的66例窒息新生儿展开研究,按照随机数字表法分为两组,对照组33例采用常规头罩给氧,观察组33例实施经鼻持续呼吸道正压通气。将两组的血气分析指标、治疗相关指标、治疗效果、气管插管率、并发症发生率进行比对。结果观察组患儿治疗后的PaO_2、Apgar评分高于对照组,PaCO_2低于对照组,通气时间、起效时间以及复苏时间短于对照组,差异具有统计学意义(P <0.05);观察组患儿的临床总有效率高于对照组,并发症发生率低于对照组,差异具有统计学意义(P <0.05)。结论对新生儿窒息采用经鼻持续呼吸道正压通气治疗可促进其血气指标的改善,提升抢救效果,还可降低气管插管率、并发症发生率。 Objective To study the effect of nasal continuous positive airway pressure on the rate of tracheal intubation and complications in the treatment of neonatal asphyxia.Methods 66 asphyxiated newborns from August 2018 to August 2019 were included in the study.According to the random number table,they were divided into two groups.33 cases in the control group were given oxygen by conventional head mask,and 33 cases in the observation group were given continuous positive airway pressure ventilation through nose.The blood gas analysis index,treatment related index,treatment effect,endotracheal intubation rate and complication rate of the two groups were compared.Results The scores of PaO2 and Apgar in the observation group were higher than those in the control group,PaCO2 was lower than that in the control group,ventilation time,onset time and recovery time were shorter than those in the control group.The difference was statistically significant(P<0.05).The total clinical efficiency of the observation group was higher than that in the control group,and the incidence of complications was lower than that in the control group.The difference was statistically significant(P<0.05).Conclusion The treatment of neonatal asphyxia with nasal continuous positive airway pressure can improve the blood gas index,improve the rescue effect,and reduce the rate of tracheal intubation and complications.
作者 卢煜明 张爱民 徐霭贤 徐国明 LU Yu-ming;ZHANG Aimin;XU Ai-xian(Foshan Second People's Hospital,Foshan 528000,China)
出处 《中国处方药》 2020年第12期167-168,共2页 Journal of China Prescription Drug
关键词 新生儿窒息 经鼻持续呼吸道正压通气 气管插管 并发症 Neonatal asphyxia Nasal continuous positive airway pressure ventilation Endotracheal intubation Complications
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