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纤支镜肺泡灌洗治疗对重症肺炎患儿肺功能、炎症反应的影响 被引量:1

Effect of Fiberoptic Bronchoscopic Alveolar Lavage on Pulmonary Function and Inflammatory Response in Children with Severe Pneumonia
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摘要 目的:探讨纤支镜肺泡灌洗治疗重症肺炎患儿的效果。方法:将2018年1月-2020年2月笔者所在医院收治的80例重症肺炎患儿,按照随机数字表法分为两组,对照组40例给予吸氧、平喘解痉、止咳祛痰、退热、纠正水电解质紊乱等常规治疗,研究组40例加以纤支镜肺泡灌洗治疗。比较两组临床疗效、心率恢复正常时间、呼吸恢复正常时间、咳嗽咳痰消失时间、肺部湿啰音消失时间、发热消退时间、感染控制时间、住院时间及动脉血气指标[血氧分压(PaO2)、二氧化碳分压(PaCO2)、血氧饱和度(SaO2)]。结果:研究组临床治疗总有效率(87.50%)高于对照组(67.50%),差异有统计学意义(P<0.05)。研究组心率恢复正常时间、呼吸恢复正常时间、咳嗽咳痰消失时间、发热消退时间、感染控制时间、湿啰音消失时间、住院时间均早于对照组,差异均有统计学意义(P<0.05)。干预前两组PaO2、PaCO2、SaO2水平比较差异无统计学意义(P>0.05),干预后两组PaO2、SaO2水平均高于干预前,PaCO2水平均低于干预前,且研究组各指标均优于对照组,差异均有统计学意义(P<0.05)。结论:纤支镜肺泡灌洗治疗重症肺炎患儿有助于提高临床疗效,促进临床症状改善,改善患儿肺功能。 Objective:To investigate the effect of fiberoptic bronchoscopic alveolar lavage in children with severe pneumonia.Method:From January 2018 to February 2020,80 children with severe pneumonia admitted to our hospital were divided into two groups according to random number table method.40 children in the control group were given routine treatment such as oxygen inhalation,antiasthma and spasmolysis,cough relief and expectoration,antipyretic,correction of water and electrolyte disorders,and 40 children in the study group were given fiberoptic bronchoscopic alveolar lavage treatment.The clinical efficacy,heart rate recovery time,respiratory recovery time,cough and expectoration disappearance time,lung moist rales disappearance time,fever regression time,infection control time,hospitalization time and arterial blood gas indexes (PaO2,PaCO2,SaO2) were compared between the two groups.Result:The total clinical effective rate in the study group (87.50%) was higher than that in the control group (67.50%),the difference was statistically significant (P<0.05).The heart rate recovery time,respiratory recovery time,cough and expectoration disappearance time,lung moist rales disappearance time,fever regression time,infection control time,hospitalization time in the study group were all earlier than those in the control group,the differences were statistically significant (P<0.05).There was no significant difference in the levels of PaO2,PaCO2 and SaO2 between the two groups before intervention (P>0.05),and the levels of PaO2 and SaO2 in the two groups after intervention were higher than those before intervention,PaCO2 levels in both groups were lower than those before intervention,and all indexes in the study group were better than those in the control group,the differences were statistically significant (P<0.05).Conclusion:Fiberoptic bronchoscopic alveolar lavage in children with severe pneumonia is helpful to improve the clinical efficacy,promote the improvement of clinical symptoms,and improve the pulmonary function of children.
作者 李小丽 LI Xiaoli(Shenzhen Longgang Maternal and Child Health Hospital,Shenzhen 518000,China)
出处 《中外医学研究》 2020年第35期147-149,共3页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 纤支镜肺泡灌洗 重症肺炎 临床疗效 肺功能 炎症反应 Fiberoptic bronchoscopic alveolar lavage Severe pneumonia Clinical curative effect Lung function Inflammatory response
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