摘要
微循环障碍是重症急性胰腺炎(severe acute pancreatitis,SAP)的重要发病机制之一,总结有关中药复方和单味中药通过抑制核因子κB(NF-κB)信号通路改善胰腺组织微循环,从而治疗SAP的研究,发现当前研究以动物实验为主,临床研究较少且缺乏统一有效的观察指标及疗效判断标准。因此,今后需开展多中心、大样本的临床随机试验。参考文献39篇。
Microcirculatory disorders are important mechanism of severe acute pancreatitis(SAP).By summarizing the studies on treatment of SAP by inhibiting the NF-κB signaling pathway to improve the microcirculation of pancreatic tissue with traditional Chinese medicine(TCM)compound and single medicinal of TCM,it can be concluded that the current studies solely focuses on animal experiments,and there are few clinical studies with unified and effective observation indicators and efficacy judgment standard.Therefore,multi-center,large-sample and randomized clinical trials are needed in the future.There are 39 references.
作者
廖健思
边志远
文玲
王建超
农国勇
田玉玲
LIAO Jiansi;BIAN Zhiyuan;WEN Ling;WANG Jianchao;NONG Guoyong;TIAN Yuling(Guangxi University of Chinese Medicine,Nanning 530001,China;Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine,Nanning 530011,China)
出处
《山东中医杂志》
2021年第1期105-108,共4页
Shandong Journal of Traditional Chinese Medicine
基金
广西自然科学基金项目(编号:2015jjAA40320)
全国名老中医传承工作室(雷力民名老中医传承工作室)建设项目
广西中医药大学研究生创新课题(编号:YCSY2018043)。
关键词
重症急性胰腺炎
中医药
核因子ΚB
微循环障碍
安胰颗粒
清胰汤
大黄
黄芩
severe acute pancreatitis
traditional Chinese medicine
NF-κB
microcirculation disorders
Anyi Granules
Qingyi Decoction
Dahuang(Rhei Radix Et Rhizoma)
Huangqin(Scutellariae Radix)
