摘要
目的:探究洗心汤加减配合醒脑开窍针法治疗一氧化碳中毒后痴呆的临床效果。方法:选取2018年3月-2019年2月间我院收治的28例因一氧化碳(CO)中毒后导致痴呆的患者作为本次研究的对象。将其随机分为观察组(14例)对照组(14例),两组患者均接受依达拉奉等常规基础治疗,同时给予洗心汤,观察组在此基础上给以醒脑开窍针法联合治疗。观察两组患者治疗前后的有效率及对比两组间的有效率;通过简易精神状态量表(Mini-Mental State Examination,MMSE)的评分简单评估患者治疗前后及两组治疗效果。评价两组患者治疗前后的症状轻重程度,评价两组患者中沉默寡言、表情呆滞、倦怠乏力或是头昏胀不适等症状并对两组患者的症状进行评分。通过观察患者治疗前后血清中丙二醛(Malondialdehyde,MDA)、超氧化物气化酶(Superoxide Dismutase,SOD)水平评价治疗效果。结果:通过研究,观察组的总有效率明显高于对照组。两组间治疗前MMSE评分的差异无统计学意义(P>0.05),两组治疗后的MMSE评分均高于治疗前,除此之外,观察组中的评分比对照组高。观察组患者症状的改善力度明显比对照组大,并且观察组中的症状评分明显低于对照组。观察组中治疗后MDA、SOD水平明显高于治疗前及对照组。结论:通过研究结果可得出,一氧化碳中毒导致的痴呆在洗心汤加减的治疗下可以得到很好的缓解,当配合醒脑开窍针法治疗时可取得更好的临床效果,早期用于一氧化碳中毒引起的痴呆患者可增加痊愈率。
Objective:To explore the clinical effects of the Xixin decoction(洗心汤)plus the Xingnao Kaiqiao acupuncture(醒脑开窍针法)on dementia after carbon monoxide poisoning.Methods:28 cases were randomly divided into the observation group(14 cases)and the control group(14 cases).The groups received conventional basic treatment such as edaravone,and were given the Xixin decoction at the same time.On this basis,the observation group was given the Xingnao Kaiqiao acupuncture.Results:The total efficiency in the observation group was significantly higher than the control group.The difference in MMSE scores before treatment between the groups was not statistically significant(P>0.05).After treatment,the MMSE scores in the groups were both higher than before,and the scores in the observation group were higher compared with the control group.The symptom amelioration in the observation group was significantly greater than the control group,and the symptom score in the observation group was significantly lower than the control group.The levels of MDA and SOD after treatment in the observation group were significantly higher than before and the control group.Conclusion:It can be concluded from the results of the study that the Xixin decoction can alleviate clinical symptoms of dementia after carbon monoxide poisoning well.The Xixin decoction plus the Xingnao Kaiqiao acupuncture on dementia after carbon monoxide poisoning can obtain better clinical effects,and increase the recovery rate in the early stage of the desease.
出处
《中医临床研究》
2020年第32期68-71,共4页
Clinical Journal Of Chinese Medicine
关键词
洗心汤加减
醒脑开窍针法
一氧化碳中毒
痴呆
The Xixin decoction
The Xingnao Kaiqiao acupuncture
Carbon monoxide poisoning
Dementia
