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高压氧辅助治疗对胃癌伴失眠患者心理状态、睡眠质量及生命质量的影响研究 被引量:4

Effects of Hyperbaric Oxygen Adjuvant Therapy on Psychological States,Sleep and Life Quality of Patients with Gastric Cancer and Insomnia
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摘要 目的:探究高压氧辅助治疗对胃癌伴失眠患者心理状态、睡眠质量及生命质量的影响。方法:选取2018年9月至2019年11月南京鼓楼医院集团宿迁市人民医院收治的胃癌化疗伴失眠患者50例作为研究对象,按照随机数字表法分为观察组和对照组,每组25例,均给予FOLFOX方案化疗,对照组给予阿普唑仑治疗,观察组在对照组化疗方案基础上辅助高压氧治疗,比较2组患者抑郁自评量表(SDS)及焦虑自评量表(SAS)评分、匹兹堡睡眠质量指数(PSQI)评分及生命质量评定表(QLQ-C30)评分。结果:经过治疗后2组患者SDS、SAS评分及PSQI各维度评分显著降低,QLQ-C30各维度评分明显提高,且观察组改善更为明显(P<0.05)。结论:高压氧辅助治疗胃癌伴失眠患者可改善其心理状态,提高睡眠质量和生命质量。 Objective:To explore the effects of hyperbaric oxygen adjuvant therapy on psychological states,sleep and life quality of patients with gastric cancer and insomnia.Methods:Fifty patients with gastric cancer and insomnia who were admitted and treated in the hospital between September 2018 and November 2019 were selected as the research subjects.They were divided into the experimental group and the control group by random number table method,25 cases in each group.All patients were given FOLFOX regimen chemotherapy.On this basis,the control group was treated with alprazolam,and the experimental group was treated with hyperbaric oxygen therapy based on the treatment of control group.The self-rating depression scale(SDS),self-rating anxiety scale(SAS),Pittsburgh sleep Quality index(PSQI)and quality of life(QLQ-C30)scores of the two groups were compared.Results:After treatment,the SDS,SASand PSQI scores of both groups were significantly decreased,the QLQ-C30 scores were significantly improved.Besides,the improvement was more obvious in the experimental group(P<0.05).Conclusion:Hyperbaric oxygen adjuvant therapy of patients with gastric cancer and insomnia can improve their psychological states,sleep quality and quality of life.
作者 朱莹 ZHU Ying(Department of Oncology,Nanjing drum tower hospital group suqian people′s hospital,The affiliated Suqian Hospital of Xuzhou Medical University,Suqian 223800,China)
出处 《世界睡眠医学杂志》 2020年第11期1868-1869,共2页 World Journal of Sleep Medicine
关键词 高压氧 胃癌 失眠 心理状态 睡眠质量 生命质量 Hyperbaric oxygen Gastric cancer Insomnia Psychological state Sleep quality Quality of life
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