摘要
目的了解2016-2017年北京市门头沟区发热呼吸道症候群(febrile respiratory illnesses,FRI)病原谱构成和流行情况。方法采集哨点医院发热呼吸道感染病例的上、下呼吸道样本,利用多重实时荧光PCR法对发热呼吸道症候群(FRI)17种病原体进行核酸检测,并对流行特征进行分析。结果591例发热呼吸道感染病例中检出阳性病原体115例(19.46%),双重感染5份,共检出14种病原体,排名前三位的为流感病毒(28.33%)、腺病毒(15.83%)和肠道病毒(13.33%)。按年龄将病例分成5组,不同年龄组病例样本的阳性检出率差异无统计学意义(χ2=6.158,P>0.05)。<5岁婴幼儿和≥60岁老年人是呼吸道病原体的主要感染人群。结论门头沟区FRI病原谱以流感病毒、腺病毒和肠道病毒为主,婴幼儿和老年人是防控的重点人群。加强呼吸道病原体监测对保护易感人群和防控传染病具有重要意义。
Objective To investigate the pathogenic spectrum constitution and the epidemic situation of febrile respiratory illnesses in Mentougou district of Beijing,from 2016 to 2017.Methods Upper and lower respiratory specimens were collected from patients with respiratory tract infection.Nucleic acid testing of 17 pathogens were taken by multiplex real-time PCR.Epidemiological characteristics were also analyzed.Results Among the 591 cases of febrile respiratory illnesses,115 cases(19.46%)were test positive and 5 cases were double infected.14 pathogens were detected.The top three pathogens were influenza virus(28.33%),respiratory adenovirus(15.83%)and enterovirus(13.33%).No statistical significant differences of positive rate was observed between different age groups(χ2=6.158,P>0.05).Children under 5 years old and people over 60 years age were the major infected groups of the febrile respiratory illnesses.Conclusions The pathogenic spectrum of febrile respiratory illnesses was mainly consisted of influenza virus,adenovirus and enterovirus,in Mentougou district.Children and the elderly were the key population of prevention and control.Therefore,strengthening the monitoring of respiratory pathogens is of great significance for the protection of risk population and for the prevention and control of febrile respiratory illnesses.
作者
宋景红
张铁钢
刘海涛
张博文
SONG Jing-hong;ZHANG Tie-gang;LIU Hai-tao;ZHANG Bo-wen(Mentougou District Center for Disease Control and Prevention,Beijing 102300,China)
出处
《首都公共卫生》
2020年第5期256-258,共3页
Capital Journal of Public Health
基金
国家科技重大专项(编号:2017ZX10103004)。
