摘要
目的:观察独活寄生汤加减联合浮针治疗膝骨性关节炎(KOA)的临床疗效。方法:将符合纳入标准82例KOA患者按随机数字表分为对照组和观察组,每组41例。对照组给予塞来昔布胶囊口服治疗,观察组在对照组治疗的基础上给予独活寄生汤加减联合浮针治疗,对比两组治疗前后的中医证候评分、WOMAC评分、血清肿瘤坏死因子(TNF-α)、白介素-6(IL-6)、超敏C反应蛋白(hs-CRP)水平。结果:治疗后两组的中医证候评分、WOMAC评分、血清肿瘤坏死因子(TNF-α)、白介素-6(IL-6)、超敏C反应蛋白(hs-CRP)水平均下降,差异有统计学意义(P<0.05);且观察组优于对照组,差异有统计学意义(P<0.05)。结论:独活寄生汤加减联合浮针可以有效的缓解患者疼痛,改善膝关节功能,降低炎性因子水平,提高患者生活质量。
Objective:To observe the clinical effect of Duhuo Jisheng Decoction combined with floating needling in the treatment of knee osteoarthritis(KOA).Methods:82 patients with KOA met the inclusion criteria were randomized into the control group(n=41)and the observation group(n=41).The control group was treated with Celecoxib Capsules;on which basis,the observation group was also treated with Duhuo Jisheng Decoction combined with floating needling.The scores of TCM syndrome and WOMAC,and the serum levels of TNF-α,IL-6 and hs-CRP were compared between before and after the treatment in the two groups.Results:The scores of TCM syndrome and WOMAC,as well as the serum levels of TNF-α,IL-6 and hs-CRP were significantly decreased after the treatment compared to those before the treatment in the two groups;the decreases in the observation group were more significant(P<0.05).Conclusion:Duhuo Jisheng Decoction combined with floating needling can effectively relieve the pain,improve knee function,reduce levels of inflammatory factors,and improve life quality of the patients in the treatment of KOA.
作者
李洪涛
王志超
孙晓伟
王波
彭宇飞
LI Hongtao;WANG Zhichao;SUN Xiaowei;WANG Bo;PENG Yufei(Heilongjiang University of Chinese Medicine, Harbin 150040, China;The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150040, China)
出处
《中医药信息》
2021年第1期50-53,共4页
Information on Traditional Chinese Medicine
基金
黑龙江省自然科学基金项目(H2017058)
黑龙江省博士后资助项目(LHB-Z12265)
国家教育部海外合作项目“春晖计划”(Z2009-1-15031)
黑龙江省教育厅课题(12511499)
黑龙江省中医管理局课题(ZHY12-Z067)
黑龙江中医药大学校基金课题(035148)。
关键词
独活寄生汤
浮针
膝骨性关节炎
Duhuo Jisheng Decoction
Floating needling
Knee osteoarthritis
