摘要
肝硬化是慢性乙型肝炎、丙型肝炎、酒精性及非酒精性脂肪性肝病等多种慢性肝病的共同结局,主要表现为肝细胞功能障碍和门静脉高压症及其并发症。结合病史,可根据内镜、影像、生化、血液学指标做出肝硬化的临床诊断。肝硬化的诊断应尽可能明确病因、疾病分期和肝功能分级;治疗应尽可能包括病因治疗、综合支持治疗和针对各种并发症的治疗措施,并对患者进行长期随访和监测,以达到延缓疾病进展、延长生存期和提高生活质量的目标。
Liver cirrhosis is the end-stage of various liver diseases including chronic hepatitis B,hepatitis C,alcoholic and nonalcoholic fatty liver diseases,with the main manifestations of hepatocyte dysfunction,portal hypertension and a series of complications.A clinical diagnosis of liver cirrhosis can be made based on medical history and the results of endoscopy,radiology,biochemistry,and hematological tests.Etiology,disease stage,and liver function reserve should be clarified for the diagnosis of liver cirrhosis.Treatment should include etiological therapy,comprehensive supportive therapy,and measures for various complications,aiming to prolong survival and improve quality of life.Long-term follow-up should be performed to monitor disease progression,evaluate therapeutic efficacy.
作者
贾继东
JIA Jidong(Liver Research Center,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China)
出处
《临床肝胆病杂志》
CAS
北大核心
2021年第1期12-13,共2页
Journal of Clinical Hepatology
关键词
肝硬化
门静脉高压
治疗学
疾病管理
Liver Cirrhosis
Portal Hypertension
Therapeutics
Disease Management
