摘要
目的探讨慢性阻塞性肺疾病评估测试(CAT)评分在慢性阻塞性肺疾病(COPD)患者病情及疗效评估中的应用价值。方法分析147例因COPD急性加重住院患者的资料,患者入院后48 h内进行CAT评分、肺功能及血气分析检测,出院2个月后随访,其中有79例患者完成了CAT评分与肺功能的复测。对结果进行统计分析。结果 147例患者的CAT评分与FEV1%呈负相关(r=-0.703,P<0.01),与PaO2呈负相关(r=-0.378,P<0.01),与PaCO2呈正相关(r=0.323,P<0.01)。79例患者出院2个月后的CAT评分与FEV1%呈负相关(r=-0.658,P<0.01);有呼吸衰竭组患者的CAT评分显著高于无呼吸衰竭组[(21.8±5.4)vs(17.0±5.8),P<0.01],前者FEV1%显著低于后者[(38.9±16.9)vs(55.9±18.7),P<0.01];随着肺功能分级的增加,CAT评分逐渐升高,CAT评分在4组肺功能组间两两比较均有显著性差异;79例患者出院2个月后的CAT评分较急性加重入院时有显著下降[(14.5±4.8)vs (17.5±5.7),P<0.01],FEV1%较急性加重入院时有显著升高[(62.2±22.1)vs(53.9±20.4),P<0.01]。结论 CAT评分对COPD患者病情严重程度及治疗效果的评价具有一定的临床价值,可作为监测COPD患者病情及疗效的有效工具。
Objective To explore the application value of CHRONIC obstructive pulmonary disease assessment test(CAT)score in the assessment of the condition and efficacy of COPD patients. Methods The data of 147 patients hospitalized due to acute exacerbation of COPD were analyzed. CAT score,lung function and blood gas analysis were performed within 48 h after admission. Follow-up was conducted 2 months after discharge,and CAT score and lung function were retested in 79 patients. Analyze the results statistically.Results The CAT scores of 147 patients were negatively correlated with FEV1%(r=-0.703,P<0.01),negatively correlated with PaO2(r=-0.378,P<0.01),positively correlated with Pa CO2(r=0.323,P<0.01),and negatively correlated with FEV1%(r=-0.658,P<0.01)2 months after discharge. The CAT score of patients with respiratory failure was significantly higher than that of patients without respiratory failure [(21.8±5.4)vs(17.0±5.8),P<0.01],and the percentage of FEV1 in the former group was significantly lower than that in the latter group [(38.9±16.9)vs(55.9±18.7),P<0.01]. With the increase of pulmonary function grade,CAT score gradually increased,and there were statistically significant differences in CAT score between the four lung function groups. The CAT score of 79 patients 2 months after discharge was significantly lower than that at admission with acute exacerbation [(14.5±4.8)vs(17.5±5.7),P<0.01],and the proportion of FEV1 in the estimated value % was significantly higher than that at admission with acute exacerbation [(62.2±22.1)vs(53.9±20.4),P<0.01].Conclusion CAT score has clinical application value in evaluating the severity and therapeutic effect of COPD patients,and can be used as an effective tool to monitor the condition and curative effect of COPD patients.
作者
时延伟
张二明
郭伟安
向平超
Shi Yanwei;Zhang Erming;Guo Weian(The Shougang Hospital of Peking University,Beijing 100144)
出处
《基层医学论坛》
2021年第2期152-155,共4页
The Medical Forum
基金
北京市石景山区医学重点学科建设项目(20130003)。
关键词
慢性阻塞性肺疾病
慢性阻塞性肺疾病评估测试
肺功能
疗效评估
Chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease assessment test
Lung function
Therapeutic effect evaluation
