摘要
目的探究乌司他丁、热毒宁注射液治疗暑厥证型热射病患者的效果。方法选取我院2019年1月-2020年8月期间急诊科收治的30例暑厥证型热射病患者作为研究对象,所有患者均接受乌司他丁与热毒宁注射液治疗,记录患者凝血功能与炎症因子水平变化情况。结果患者治疗1d、2d与7d后,活化部分凝血活酶时间(APPT)、凝血酶原时间(PT)均低于治疗前,且纤维蛋白原(Fib)水平高于治疗前,差异显著(P<0.05)。患者治疗1d、2d与7d后,炎症因子水平均低于治疗前,差异显著(P<0.05)。结论在暑厥证型热射病患者治疗中应用乌司他丁与热毒宁注射液,可改善凝血功能,并减轻炎症反应。
Objective To investigate the effect of ulinastatin and Retoxining injection on heat stroke patients with heat stroke syndrome. Methods Thirty patients with heatstroke syndrome admitted to the emergency department of our hospital from January 2019 to August 2020 were selected as study subjects. All patients were treated with ulinastatin and Retoxining injection,and changes in coagulation function and inflammatory factors were recorded.Results The activated partial thromboplastin time(APPT)and prothrombin time(PT)were lower than those before treatment,and the fibrinogen(Fib)level was higher than that before treatment(P<0.05). After treatment on 1 d,2 D and 7 d,inflammatory factors were lower than those before treatment,with significant differences(P<0.05). Conclusion Ulinastatin and retoxining injection can improve the coagulation function and reduce inflammation in the treatment of heat stroke patients with heatstroke syndrome.
作者
朱亚君
石剑锋
高良东
Zhu Yajun;Shi Jianfeng;Gao Liangdong(The Affiliated Hospital of Jiujiang University,Jiujiang,Jiangxi 332000;The Sixth People's Hospital of Jiujiang City,Jiangxi 332000)
出处
《基层医学论坛》
2021年第2期166-168,共3页
The Medical Forum
基金
江西省卫生计生委科技计划(20197203)。
关键词
热射病
暑厥证
乌司他丁
热毒宁
凝血功能
炎症反应
Heat stroke
Heatstroke syndrome
Ulinastatin Reduning
Coagulation function
Inflammatory response
