摘要
目的:探讨多种膀胱肿瘤整块切除术治疗非肌层浸润性膀胱癌(NMIBC)的临床疗效。方法:回顾性分析2016年1月~2019年2月合肥市第八人民医院就诊的NMIBC病例。126名患者分别给予经尿道膀胱肿瘤电切术(TURBT)、等离子膀胱肿瘤整块切除术(PK-ERBT)和钬激光膀胱肿瘤整块切除术(HoL-EBRBT)。结果:PK-ERBT和HoL-EBRBT组患者较TURBT组患者具有更少的手术时间、术后住院时间、手术并发症以及术后肿瘤复发率(P<0.05)。多因素Cox回归显示,整块切除术(PK-ERBT组和HoL-EBRBT组)是影响复发的保护因素(P<0.05),而广基膀胱肿瘤是肿瘤复发的危险因素(P<0.05)。结论:膀胱肿瘤整块切除术可能是治疗NMIBC病例安全且有效的方法。
Objective:To observe the clinical effect of multiple en-bloc resection in the treatment of non-muscular invasive bladder cancer(NMIBC).Methods:Retrospective analysis was performed in 126 patients of NMIBC undergone transurethral resection of bladder tumors(TURBT),bipolar plasma kinetic en-bloc resection of bladder tumor(PK-ERBT)or holmium laser en-bloc transurethral resection of bladder tumor(HoL-EBRBT)in our hospital between January 2016 and February 2019.Results:Patients treated by PK-ERBT or HoL-EBRBT had shorter operative time,reduced postoperative hospital stay,lower complications associated with operation and incidence of postoperative tumor recurrence than those treated by TURBT(P<0.05).Multivariate Cox regression analysis showed that en-block resection(PK-ERBT and HoL-EBRBT groups)was a protective factor for recurrence(P<0.05),whereas sessile tumor in the bladder was a risk factor for tumor recurrence(P<0.05).Conclusion:En-bloc resection may be effective and safe approach to treatment of NMIBC.
作者
伍庆余
李旭东
陈兵
魏九林
宁贤友
唐智国
WU Qingyu;LI Xudong;CHEN Bing;WEI Jiulin;Ning Xianyou;TANG Zhiguo(Department of Urology,The Eighth People′s Hospital of Hefei,Chaohu 238000,China)
出处
《皖南医学院学报》
CAS
2021年第1期43-46,共4页
Journal of Wannan Medical College
基金
合肥市卫生健康委员会应用医学研究项目。
关键词
非肌层浸润性膀胱癌
整块切除术
膀胱肿瘤
non-muscle invasive bladder cancer
en-bloc resection
bladder tumor
