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全身和硬膜外麻醉对外科手术患者术后短期认知功能的影响

Effects of General and Epidural Anesthesia on Short-term Postoperative Cognitive Function of Surgical Patients
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摘要 目的探讨全身麻醉和硬膜外麻醉对手术患者术后短期认知功能的影响。方法选取2018年1月至2019年1月在大连市友谊医院外科就诊的80例需要麻醉的患者,随机分为试验组和对照组,对照组40例采取全身麻醉治疗,试验组40例使用硬膜外麻醉,记录两组患者的蒙特利尔认知评估表评分及POCD(认知功能障碍)发生率,以比较两组患者在术后不同时间内的认知障碍发生率。结果两组患者的评分得分情况,试验组术后4 h、6 h MoOCA评分优于对照组,差异有统计学意义(P<0.05),试验组术后24 h后MoCA评分与对照组比较无差异(P>0.05)。两组术后24 h的POCD发生率差异无统计学意义(P>0.05)。结论对患者采取硬膜外麻醉,造成的短期认知功能障碍影响与全身麻醉相比要更轻,且认知功能障碍的发生率比较低,值得在临床推广。 Objective To investigate the effects of general anesthesia and epidural anesthesia on postoperative short-term cognitive function of patients.Methods From January 2018 to January 2019 in Dalian Friendship Hospital,80 cases of surgical treatment to patients with anesthesia,were randomly divided into experimental group and control group,control group 40 cases treated with general anesthesia,the experimental group 40 cases with epidural anesthesia,records of two groups of patients with montreal cognitive assessment scale and POCD(post operative cognitive dysfunction)incidence,to compare two groups of patients in the incidence of postoperative cognitive impairment in different time.Results Grading scores results:the experimental group postoperative 4 h,6 h MOCA score is better than that of control group,the difference was statistically significant(P<0.05),the experimental group after 24 h after MOCA score compared with the control group no difference(P>0.05),there was no significant difference in the incidence of POCD between the two groups(P>0.05).Conclusion Compared with general anesthesia,the effect of epidural anesthesia on short-term cognitive dysfunction in patients is lighter,and the incidence of cognitive dysfunction is lower,which is worthy of clinical promotion.
作者 王辉 WANG Hui(Department of Anesthesiology,Dalian Friendship Hospital,Dalian 116001,China)
出处 《中国医药指南》 2020年第35期93-94,共2页 Guide of China Medicine
关键词 全身麻醉 硬膜外麻醉 术后认知功能障碍 蒙特利尔认知评估 General anesthesia Epidural anesthesia Post operative congnitive dysfuntion Montreal cognitive assessment
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