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肝衰竭合并侵袭性真菌病的诊断策略

Diagnostic strategy of liver failure with invasive fungal disease
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摘要 肝衰竭患者发生侵袭性真菌病(IFD)的危险性增加,致死率增加,早期诊断、及时治疗是改善预后的关键。笔者梳理了肝衰竭合并IFD的流行情况及危险因素、肝衰竭患者的早期识别、肝衰竭合并IFD的诊断、中医对肝衰竭合并真菌感染的认识等内容。肝衰竭患者凝血机制差,获取病理确诊较为困难,详细分析患者的危险因素、早期识别临床特征、及时进行血液/体液微生物学检测是早期诊断的重要策略。 The patients with liver failure have an increased risk of invasive fungal disease(IFD)which leads to high mortality.Early diagnosis and timely treatment are important to improve the prognosis of patients.Here,the authors reviewed the prevalence,the risk factors,the early identification,the diagnostic methods,and the diagnosis criteria of liver failure with IFD.The understanding of Chinese medicine on liver failure with fungal infection was addressed as well.It is difficult to obtain a proved diagnosis because of poor coagulation of patients with liver failure.Detailed analysis of risk factors,early identification of clinical features,and detection of microbiology are important strategies for a probable and possible diagnosis.
作者 李丽 李秀惠 陈煜 LI Li;LI Xiu-hui;CHEN Yu(Integrated traditional Chinese and western medicine center,Beijing You'An hospital,capital medical university,Beijing 100069,China;不详)
出处 《中西医结合肝病杂志》 CAS 2021年第1期7-10,20,共5页 Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
基金 北京佑安医院中青年人才孵育项目(No.YNKTTS20180127) “扬帆计划”重点医学专业项目(No.ZYLX201819)。
关键词 肝衰竭 真菌感染 诊断策略 liver failure invasive fungal disease diagnostic methods diagnostic strategy
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