摘要
目的探讨不同类型食管支架置入治疗食管癌-食管气管瘘的疗效及安全性。方法选取食管癌放疗后食管气管瘘患者100例,按治疗置入支架的类型分为2组,研究组(n=50例)置入新型超覆膜支架,对照组(n=50例)置入不锈钢金属支架。观察2组患者生活质量评分、生存期、并发症等。结果2组患者治疗前KPS评分比较,无明显差别异(P>0.05);治疗后研究组KPS评分和生活质量改善有效率均显著高于对照组,差异具有统计学意义(P<0.05)。术后2组患者胸骨后疼痛、支管移位、食管反流等并发症发生情况比较,研究组显著少于对照组,差异具有统计学意义(P<0.05)。研究组肺部感染控制有效率显著高于对照组,生存期显著长与对照组,差异具有统计学意义(P<0.05)。结论新型超覆膜支架置入是治疗食管癌-食管气管瘘的一种安全、有效的方法,能提高患者的生活质量、延长食管癌-食管气管瘘患者生存期、控制肺部感染、减少并发症的发生,具有很好的临床意义,值得广泛推广和应用。
Objective To investigate the efficacy and safety of different types of esophageal stent implantation in the treatment of esophageal cancer-esophageal tracheal fistula.Methods 100 patients with esophageal fistula after radiotherapy for esophageal cancer were selected and divided into 2 groups according to the type of stent implanted in the treatment.The control group(n=50 cases)was implanted with stainless steel metal stents to observe the quality of life score,survival period,and complications of the 2 groups of patients.Results There was no significant difference in KPS scores before treatment between the 2 groups of patients(P>0.05);After treatment,the effective rate of KPS score and quality of life improvement in the study group was significantly higher than that in the control group,and the difference was statistically significant(P<0.05);Compared the occurrence of complications such as retrosternal pain,branch displacement,and esophageal reflux between the two groups after surgery,the study group was significantly less than the control group,and the difference was statistically significant(P<0.05);The effective rate of lung infection control in the study group was significantly higher than that of the control group,and the survival period was significantly longer than that of the control group,and the difference was statistically significant(P<0.05).Conclusion The new super stent graft is a safe and effective method for the treatment of esophageal cancer-esophageal tracheal fistula,which can improve the quality of life of patients,prolong the survival time of patients with esophageal cancer-esophageal tracheal fistula,control lung infections,and reduce complications,and it has good clinical significance,it is worthy of widespread promotion and application.
作者
王媛
惠双
万里新
郭宏强
WANG Yuan;HUI Shuang;WAN Lixin(Nanyang Central Hospital,Nanyang,473000)
出处
《实用癌症杂志》
2021年第1期77-79,88,共4页
The Practical Journal of Cancer
基金
河南省青年科学基金项目(编号:81101797)。
关键词
食管癌
食管气管瘘
金属支架
新型超覆膜支架
生活质量
Esophageal cancer
Esophago-tracheal fistula
Metal stent
New super-membrane stent
Quality of life
