摘要
目的:观察二十五味珊瑚丸联合阿司匹林对急性脑梗死患者的应用效果。方法:回顾性分析2016年1月—2020年2月本院收治的80例急性脑梗死患者临床资料,根据治疗方案不同进行分组,将40例使用二十五味珊瑚丸联合阿司匹林、阿托伐他汀治疗的患者纳入观察组,将40例使用阿司匹林联合阿托伐他汀治疗的患者纳入对照组,两组均治疗60 d。比较两组治疗前、治疗60 d后的简易智力状态检查量表(MMSE)评分、神经功能缺损评分(NIHSS)、纤维蛋白原(FIB)及血小板聚集指数。结果:治疗前,两组MMSE、NIHSS评分及FIB、血小板聚集指数对比,差异无统计学意义(P>0.05);治疗60 d后,两组MMSE评分均较治疗前升高、NIHSS评分、FIB、血小板聚集指数均较治疗前降低,且观察组变化大,差异有统计学意义(P<0.05)。结论:急性脑梗死患者采用二十五味珊瑚丸联合阿司匹林治疗可以促进神经功能恢复,提高认知功能,改善机体高凝状态,值得临床推广。
Objective:To analyze the application effect of twenty-five ingredients coral pill combined with aspirin on patients with acute cerebral infarction.Methods:The clinical data of 80 patients with acute cerebral infarction who were admitted in hospital from January 2016 to February 2020 were retrospectively analyzed.They were grouped according to different treatment regimens,and 40 patients who were treated with twenty-five ingredients coral pill combined with aspirin were included in the observation.40 patients who were treated with aspirin and atorvastatin were included in the control group,and both groups were treated for 60 days.Before the treatment,at 60 days after treatment,the Mini-Mental State Examination Scale(MMSE)score,Neurological Impairment Score(NIHSS),fibrinogen(FIB)and platelet aggregation index were compared.Results:Before treatment,compared MMSE,NIHSS scores,FIB and platelet aggregation index between the two groups,the difference was not statistically significant(P>0.05);after 60 days of treatment,the MMSE scores of both groups were higher than before treatment,NIHSS score,FIB,the aggregation index of platelets was decreased compared that before treatment,and the observation group changed significantly,the difference was statistically significant(P<0.05).Conclusion:The treatment of acute cerebral infarction patients with twenty-five ingredients coral pill combined with aspirin can promote the recovery of neurological function,improve cognitive function,and improve the body’s hypercoagulable state,which is worthy of clinical promotion.
作者
谭金长
TAN Jinchang(The Traditional Chinese Medicine Hospital of Yudu County,Yudu Jiangxi 342300,China)
出处
《药品评价》
CAS
2020年第24期41-43,共3页
Drug Evaluation
关键词
脑梗死
二十五味珊瑚丸
阿司匹林
神经功能
认知功能
凝血功能
Cerebral Infarction
Twenty-five Ingredients Coral Pill
Aspirin
Nerve Function
Cognitive Function
Coagulation Function
