摘要
目的探讨保留12点黏膜法经尿道前列腺剜除术(TUERP)治疗高危良性前列腺增生(BPH)的疗效。方法选取2018年1月至2019年6月在该院治疗的高危BPH患者104例,根据随机数字表法分为对照组与观察组,各52例。对照组采取常规TUERP治疗,观察组采用保留12点黏膜法TUERP治疗;比较两组患者围术期相关指标,术后12个月并发症发生情况,以及治疗前及治疗后12个月国际前列腺症状评分(IPSS)、最大尿流率(Qmax)、残余尿量(PVR)和生存质量测定量表简表(QOL-BREF)评分。结果观察组手术时间、术中出血量、膀胱冲洗时间、导尿管留置时间明显小于对照组(P<0.05);观察组术后12个月并发症发生率明显低于对照组(7.69%vs.23.08%,P<0.05)。两组术前IPSS、Qmax、PVR无明显差异(P>0.05);与术前比较,术后12个月两组IPSS与PVR均明显降低(P<0.05),Qmax均明显升高(P<0.05),且观察组IPSS与PVR明显低于对照组,Qmax明显高于对照组(P<0.05)。观察组术后12个月生存质量各维度评分均高于对照组,差异有统计学意义(P<0.05)。结论采用保留12点黏膜法TUERP治疗高危BPH可提高患者疗效及生存质量,减少并发症的发生,安全性较高。
Objective To explore the efficacy and complications of transurethral enucleative resection of prostate(TUERP)with 12-o′clock mucosa retention for treating high-risk benign prostatic hyperplasia(BPH).Methods A total of 104 patients with high-risk BPH who were treated in our hospital from January 2018 to June 2019 were divided into the control group and the observation group according to random number table method.The control group was treated with conventional TUERP,and the observation group was treated with 12-o′clock mucosa retention TUERP.The perioperative indexes,incidence of complications 12 months after operation,International Prostate Symptoms Score(IPSS),maximum urine flow rate(QMAX),residual urine volume(PVR)and QOL-BREF(QOL-BREF)scores were compared between the two groups before and 12 months after treatment.Results The operative time,intraoperative blood loss,bladder irrigation time and catheter retention time of the observation group were significantly shorter than those of the control group(P<0.05).The incidence of complications 12 months after operation in the observation group was significantly lower than that in the control group(7.69%vs.23.08%,P<0.05).There were no significant differences in preoperative IPSS,Qmax and PVR between the two groups(P>0.05).Compared with preoperation,IPSS and PVR in both groups significantly decreased 12 months after operation(P<0.05),while Qmax significantly increased(P<0.05),and the change range of the observation group was significantly higher than that of the control group(P<0.05).The scores of all dimensions of life quality in the observation group were higher than those in the control group 12 months after operation,with statistical significances(P<0.05).Conclusion TUERP with 12-o′clock mucosa retention can effectively improve the quality of life and treatment effect of patients with high-risk BPH,reduce the occurrence of complications with high safety.
作者
刘鹏
姚雷
王雪松
安康
刘珍
张勇
LIU Peng;YAO Lei;WANG Xuesong;AN Kang;LIU Zhen;ZHANG Yong(Department of Urology Surgery,People′s Hospital of Liaoning Province,Shenyang,Liaoning 110016,China)
出处
《重庆医学》
CAS
2021年第2期238-241,共4页
Chongqing medicine
基金
辽宁省科学技术计划项目(2019-ZD-0401)。
关键词
前列腺增生
经尿道前列腺切除术
保留12点尿道黏膜
生活质量
治疗结果
prostatic hyperplasia
transurethral resection of prostate
preservation of 12-o′clock-urethral mucosa
quality of life
treatment outcome
