摘要
目的探讨伏立康唑联合两性霉素B滴眼剂在真菌性角膜炎中的应用价值.方法按照随机数字表法将我院78例(97眼)真菌性角膜炎患者分为观察组39例(49眼)与对照组39例(48眼).对照组给予两性霉素B滴眼剂治疗,观察组在此基础上联合伏立康唑治疗,均治疗1周.对比两组临床疗效、治疗安全性.结果观察组治疗总有效率95.92%高于对照组81.25%(P<0.05),不良反应发生率15.38%与对照组12.82%比较无差异(P>0.05).结论伏立康唑联合两性霉素B滴眼剂治疗真菌性角膜炎效果显著,且具有一定安全性.
Objective To investigate the application value of voriconazole combined with amphotericin B eye drops in fungal keratitis.Met hod According to random number table method,78 patients(97 eyes)with fungal keratitis in our hospital were divided into observation group(39 eyes)and control group(39 eyes).The control group was treated with amphotericin B eye drops,and the observation group was treated with voriconazole on this basis,all of which were treated for 1 week.The clinical efficacy and treatment safety of the two groups were compared.Resu 11 The total effective rate of the observation group was 95.92%higher than 81.25%of the control group(P<O.05),and the incidence of adverse reactions was 15.38%compared with 12.82%of the control group(P>0.05).Conclusion Voriconazole combined with amphotericin B eye drops has a significant effect in the treatment of fungal keratitis,and has a certain safety.
出处
《首都食品与医药》
2021年第1期83-84,共2页
Capital Food Medicine
