摘要
目的了解增生性玻璃体视网膜病变(PVR)近10年相关研究文献的分布规律和国际研究趋势。方法使用美国情报研究所Web of Science数据库为数据源,对2009—2018年收录的PVR相关文献的年代分布、国家和地区情况,基金资助情况,机构、期刊和作者影响力,引文情况等进行统计分析。并利用文献计量分析软件Citespace和VOSviewer进行关键词分布、聚类分析及文献共被引聚类分析。结果共检出PVR相关文献905篇,研究文献语种以英语为主,美国作者发文量最多,中国作者文献量位列第2;在所有有基金资助机构的文章中,中国国家自然科学基金位列第1;引文自2009年逐年上升,自2013年明显增多;引文数量最多的期刊为《Investigative Ophthalmology&Visual Science》,总被引频次最高的研究机构为哈佛大学,对作者进行引文量统计分析亦显示引文量排名前5位的作者均来自美国哈佛医学院眼科系、麻省眼耳医院Schepens眼科研究所。统计出高频主题词41个,聚类分析结果显示,高频主题词主要聚类于PVR的病因、危险因素、分子机制、治疗及管理4个类别;关键词网络图及Overlay图均表明病因学及危险因素是当前研究的热点,而上皮-间充质转化、转化生长因子-β和纤维化则是近几年新兴的研究领域。文献共被引聚类分析结果显示引文共聚类于12个共引组。结论PVR研究文献逐年增长,研究热点为PVR发生的分子机制、预防及神经保护等,可能为今后PVR研究的发展方向。
Objective To study the distribution of the literature and the trend of international research of proliferative vitreoretinopathy(PVR)in 10 years from 2009 to 2018.Methods Using Web of Science database of the American Institute of Scientific Information as the data source to collect literature on proliferative vitreoretinopathy published from 2009 to 2018 and a statistical analysis on the distribution of the publication time,nation and funding agency was made to figure out the institution,periodical,author with highest citations respectively among the collected literature.Meanwhile,the bibliometric analysis software Citespace and VOSviewer were employed to carry out the distribution analysis and cluster analysis of keywords as well as the co-citation cluster analysis.Results A total of 905 articles related to PVR were included,mainly in English,most of which were written by American authors,and the number of literature published by Chinese authors was ranked the second.Among all the article funding institutions,the National Natural Science Foundation of China ranked NO.1 with the most funded articles.Citations increased year by year since 2009 and increased obviously since 2013.The journal with the highest citations was Investigative Ophthalmology&Visual Science,and the research institution with the highest citations was Harvard University.The statistical analysis of the citation quantity also showed that the top five authors with the highest citations were all from Massachusetts Eye and Ear,Department of Ophthalmology,Harvard Medical School.The results of cluster analysis showed that there were 41 high-frequency subject terms,and they were mainly grouped in 4 categories,which were etiology,risk factors,molecular mechanism,treatment and management of PVR.Keywords network visualization and overlay visualization both showed that etiology and risk factors were the focus of current research,while epithelial mesenchymal transition,transforming growth factor-βand fibrosis were new research fields in recent years.The results of citation cluster analysis showed there were 12 co-citation clusters.Conclusions The literature of PVR shows an upward trend,and the researches focus on the molecular mechanism,prevention,and neuroprotection of PVR,which may be the future PVR research direction.
作者
周怀蔚
李志清
李筱荣
Zhou Huaiyu;Li Zhiqing;Li Xiaorong(Tianjin Medical University Eye Hospital,School of Optometry and Ophthalmology&Eye Institute,Tianjin 300384,China)
出处
《中华实验眼科杂志》
CAS
CSCD
北大核心
2021年第1期60-66,共7页
Chinese Journal Of Experimental Ophthalmology
基金
国家自然科学基金面上项目(81670875、81870675)
天津市滨海新区卫生健康委员会科技项目重点支持项目(2019BWKZ006)
天津市教委社会科学重大项目(2018JWZD25)。