摘要
目的分析2010—2017年铜川地区艾滋病病毒(HIV)抗体初筛阳性人群分布特征,为该地区艾滋病(AIDS)防治工作制定有针对性的控制措施提供资料支持。方法收集2010—2017年铜川地区330例HIV初筛阳性标本者作为研究对象,选择免疫蛋白印迹法(Western blot)进行HIV确证检测,分析其检测结果。结果330例HIV初筛阳性患者中,294例确证阳性,28例确证阴性,8例确证不确定。2010年确证阳性率显著低于2014—2017年,且2011年显著低于2015—2017年,差异具有统计学意义(P<0.05)。确证阳性标本人群中,男性占比高于女性;未婚和离异或丧偶占比高于已婚,年龄<18岁占比最低,18~50岁占比最高;高中文化程度占比最高,小学及以下占比最低;无业或居家占比最高,其次为服务人员。感染途径中,同性性传播占比最高,其次为异性性传播,输血或血制品传播占比最低。主动咨询检测占比最高,其次为专题调研。单纯HIV感染占比为96.26%,混合HBsAg阳性占比为2.72%,混合HCV阳性占比为1.02%。结论铜川地区AIDS疫情呈逐年上升趋势,其中HIV感染者人群以男性、未婚、离异或丧偶、青壮年、初高中、无业或居家及服务人员为主,主要传播途径为性传播,尤其同性性传播,主要通过主动咨询检测和专题调研发现,且存在肝炎病毒混合感染现象。
Objective To analyze the distribution characteristics of population with positive human immunodeficiency virus(HIV)antibody in Tongchuan region from 2010 to 2017,and to provide data support for the development of targeted control measures for acuquired immunodeficiency syndrome(AIDS)prevention and control in the region.Methods A total of 330 HIV positive samples in Tongchuan region from 2010 to 2017 were collected as the research objects.Western blot was used for HIV confirmatory test,and the test results were analyzed.Results Among 330 HIV postive patients,there were 294 cases confirmed positive,28 cases confirmed negative,and 8 cases confirmed uncertain.The confirmed positive rate in 2010 was significantly lower than that in 2014—2017,and that in 2011 was significantly lower than that in 2015—2017,and the differences were statistically significant(P<0.05).Among the confirmed positive samples,the proportion of male was higher than that of female,and the proportion of unmarried and divorced or widowed was higher than that of married;age<18 years old accounted for the lowest proportion,and 18-50 years old accounted for the highest proportion;high school education accounted for the highest proportion,and primary school and below accounted for the lowest proportion;unemployed or home accounted for the highest proportion,followed by service personnel.In the routes of infection,homosexual transmission accounted for the highest proportion,followed by heterosexual transmission,and blood transfusion or blood praluct transmission accounted for the lowest proportion.Active consulting and testing accounted for the highest proportion,followed by special research.The proportion of simple HIV infection was 96.26%,mixed HBsAg positive rate was 2.72%,and mixed HCV positive rate was 1.02%.Conclusion The epidemic situation of AIDS in Tongchuan region is increasing year by year.Among them,HIV infected people are mainly male,unmarried,divorced or widowed,young adults,middle and high school,unemployed or home-based and service personnel.The main route of transmission is sexual transmission,especially homosexual transmission.It is mainly found through active counseling and testing and special investigation,and there is a phenomenon of mixed infection of hepatitis virus.
作者
王君
杜萍萍
WANG Jun;DU Pingping(Clinical Laboratory Department,Tongchuan City Center for Disease Control and Prevention,Tongchuan 727031;Clinical Laboratory Department,People's Hospital of Tongchuan,Tongchuan 727000,China)
出处
《临床医学研究与实践》
2021年第4期28-30,共3页
Clinical Research and Practice
关键词
HIV抗体
确证实验
流行病学分析
人群分布
HIV antibody
confirmatory experiment
epidemiological analysis
population distribution
