摘要
目的探究青少年轻中度近视应用阿托品点眼的防控效果及安全性。方法选取2018年1月至2019年1月本院接收的96例青少年轻中度近视(带框架镜或不带框架镜)患者,按抽签法分观察组(阿托品点眼)与对照组(只带或不带框架镜不作其他治疗),各48例,比较两组观察指标、治疗效果与不良反应发生率。结果治疗前,裸眼视力、角膜曲率、眼压、等效球镜与眼轴比较差异无统计学意义;治疗后,观察组裸眼视力、眼压值均高于对照组,观察组角膜曲率、等效球镜与眼轴指标均低于对照组,差异具有统计学意义(P<0.05)。观察组不良反应发生率(8.33%)低于对照组(22.91%)。观察组治疗总有效率(97.91%)高于对照组(83.33%),差异有统计学意义(P<0.05)。结论采用1%阿托品眼用凝胶点眼治疗青少年轻中度近视效果显著,可明显提高视力水平,降低不良反应发生率,改善预后,提高生活质量,值得临床推广应用。
Objective To explore the prevention and control effect and safety of applying atropine to adolescents with mild to moderate myopia.Methods 96 adolescent patients with mild to moderate myopia(with or without frame glasses)received in our hospital from January 2018 to January 2019 were selected and they were divided into observation group(atropine eye drops)and control group(only with or no other treatment without frame mirror),with 48 cases in each group,the observation indexes,treatment effects and adverse reactions between the two groups were compared.Results Before treatment,there was no statistical difference in the naked eyesight,corneal curvature,intraocular pressure,equivalent spherical lens and axial axis;after treatment,the naked eye and intraocular pressure values of the observation group were higher than those of the control group,the corneal curvature,equivalent spherical lens and axial indicators of the observation group were lower than those of the control group,and the difference was statistically significant(P<0.05);the incidence of adverse reactions in the observation group(8.33%)was lower than that of the control group(22.91%),and the treatment efficiency of the observation group(97.91%)was higher than the control group(83.33%),and the difference between the groups was statistically significant(P<0.05).Conclusion The use of 1%atropine ophthalmic gel to treat adolescents with mild to moderate myopia has a significant effect,which can significantly improve visual acuity,reduce the incidence of adverse reactions,improve prognosis and quality of life.It is worthy of clinical application.
作者
张立新
朱国平
香淦媚
温贤清
黄慧炳
ZHANG Lixin;ZHU Guoping;XIANG Ganmei;WEN Xianqing;HUANG Huibing(Department of Ophthalmology,Hengli Hospital of Dongguan City,Dongguan,Guangdong,523460,China;Department of Pharmacy,Hengli Hospital of Dongguan City,Dongguan,Guangdong,523460,China)
出处
《当代医学》
2021年第6期17-20,共4页
Contemporary Medicine
基金
东莞市社会科技发展一般项目(2018507150381451)。
关键词
青少年
轻中度近视
阿托品点眼
防控效果
安全性
Adolescent
Mild to moderate myopia
Atropine injection
Prevention and control effect
Safety
