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参苓白术散联合半夏桑叶汤加减应用对肺结核患者肺功能及免疫功能的影响 被引量:2

Effect of Shenlingbaizhu Powder Combined with Banxia Sangye Decoction on Lung Function and Immune Function in Patients with Pulmonary Tuberculosis
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摘要 目的分析参苓白术散联合半夏桑叶汤加减应用对肺结核患者肺功能及免疫功能的影响。方法方便选取该院2018年5月—2019年12月间收治的86例肺结核患者作为研究对象,随机将患者分为研究组和对照组,对照组采用常规内科抗结核治疗,研究组在对照组基础上采用参苓白术散联合半夏桑叶汤治疗,评价治疗3个月后的疗效情况,观察患者肺功能及免疫功能相关指标。结果研究组经过治疗后疗效为显效的比例(60.47%)明显高于对照组(37.21%),差异有统计学意义(χ^2=4.650,P=0.031),研究组治疗后FEV1、FVC及FEV1/FVC(2.59±0.71)L、(4.05±0.92)L、(88.53±9.26)%均高于对照组(2.13±0.42)L、(3.61±0.75)L、(80.46±8.65)%,差异有统计学意义(t=3.657、2.431、4.176,P<0.05),研究组治疗后CD4+、CD4+/CD8+水平(0.49±0.08)、(1.67±0.24)均高于对照组(0.42±0.07)、(1.45±0.19),而CD8+水平(0.22±0.03)低于对照组(0.27±0.05),差异有统计学意义(t=4.318、4.713、5.623,P<0.05)。结论参苓白术散联合半夏桑叶汤加减应用对肺结核患者具有较好的疗效,且可以提高患者肺功能及免疫功能。 Objective To analyze the effects of Shenlingbaizhu Powder combined with Banxia Sangye Decoction on lung function and immune function in patients with tuberculosis.Methods From May 2018 to December 2019,86 cases of tuberculosis patients admitted to the hospital were conveniently selected as the research objects,and the patients were randomly divided into a study group and a control group.The control group was treated with conventional medical anti-tuberculosis treatment,and the study group was treated with Shenlingbaizhu powder combined with Sangye Decoction treatment on the basis of the control group,evaluate the curative effect after 3 months of treatment,and observe the relevant indicators of the patient’s lung function and immune function.Results After treatment,the proportion of effective efficacy in the study group(60.47%)was significantly higher than that of the control group(37.21%),the difference was statistically significant(χ^2=4.65,P=0.031).After treatment,FEV1,FVC and FEV1/FVC in the study group(2.59±0.71)L,(4.05±0.92)L,(88.53±9.26)%,higher than the control group(2.13±0.42)L,(3.61±0.75)L,(80.46±8.65)%,the difference was statistically significant(t=3.657,2.431,4.176,P<0.05),the CD4+,CD4+/CD8+levels(0.49±0.08);(1.67±0.24)of the study group after treatment were higher than those of the control group(0.42±0.07);(1.45±0.19),and the CD8+level(0.22±0.03),lower than the control group(0.27±0.05),the difference was statistically significant(t=4.318,4.713,5.623,P<0.05).Conclusion Shenlingbaizhusan combined with Banxia Sangye Decoction has a good effect on patients with tuberculosis,and can improve the lung function and immune function of patients.
作者 黄志锋 林勇 HUANG Zhi-feng;LIN Yong(Department of Traditional Chinese Medicine,Putian First Hospital,Putian,Fujian Province,351100 China)
出处 《中外医疗》 2020年第35期173-175,198,共4页 China & Foreign Medical Treatment
关键词 肺结核 参苓白术散 半夏桑叶汤 肺功能 免疫功能 Tuberculosis Shenlingbaizhusan Banxia Sangye Decoction Lung function Immune function
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