摘要
目的:探讨调理脾胃针法联合综合营养干预对糖尿病肾病(DN)患者肾功能的保护作用。方法:选取2015年3月至2017年4月北京中医医院顺义医院收治DN患者68例作为研究对象,根据治疗方法不同分为对照组(n=32)与观察组(n=36),2组患者均给予常规饮食指导和综合营养干预,均实施针刺诊疗,对照组依据消渴方取穴,观察组采用调理脾胃针法取穴,2组均以6 d为1个疗程,连续治疗6个疗程。比较2组临床疗效及治疗前后临床症状积分改善情况、血糖指标及肾功能指标水平变化。结果:治疗后观察组总有效率高于对照组(P<0.05)。治疗后2组患者临床症状总积分均明显低于治疗前,观察组明显低于对照组(P<0.01)。与治疗前比较,治疗后2组FBG、2 h PBG及HbA1c水平均明显降低,观察组低于对照组(P<0.05或P<0.01)。治疗后对照组UAER、β2-MG水平均明显降低,GFR明显升高(P<0.05或P<0.01);观察组UAER、β2-MG、BUN及Scr水平均明显降低,GFR明显升高,且2组间差异有统计学意义(P<0.01)。结论:调理脾胃针法联合综合营养干预可以明显改善DN患者临床症状,有效调节糖代谢,减少蛋白尿,延缓肾功能减退,提高总体治疗效果。
Objective:To explore the protective effect of regulating spleen and stomach acupuncture combined with integrated nutrition intervention on renal function of patients with diabetic nephropathy(DN).Methods:A total of 68 cases of patients with DN who were treated in Shunyi District Hospital of Beijing University of Traditional Chinese Medicine from March 2015 to April 2017 were divided into a control group(n=32)and an observation group(n=36)according to different treatment methods.Patients of 2 groups were given routine dietary guidance and comprehensive nutrition intervention.All patients were implemented acupuncture treatment.The control group was acupointed based on Xiaoke Formula,and the observation group was acupointed by regulating spleen and stomach acupuncture.6 d for 1 treatment course,2 groups were treated for 6 courses continuously.The clinical efficacy and the improvement of clinical symptom score,blood glucose and renal function index of the 2 groups were compared before and after treatment.Results:The total effective rate was significantly higher than that of the control group(P<0.05).After treatment,the total score of clinical symptoms in the 2 groups were significantly lower than that before treatment,the observation group was significantly lower than the control group(P<0.01).Compared with that before treatment,the levels of FBG,2 h PBG and HbA1c significantly decreased in the 2 groups after treatment,and the observation group was significantly lower than those of the control group(P<0.05 or P<0.01).The levels of UAER andβ2-MG in the control group significantly decreased,GFR significantly increased(P<0.05 or P<0.01),and the difference between the 2 groups was significant(P<0.01).Conclusion:The regulating spleen and stomach acupuncture combined with integrated nutrition intervention can significantly improve the clinical symptoms of patients with DN,effectively regulate glucose metabolism,reduce proteinuria,delay the renal dysfunction and improve the overall therapeutic effect.
作者
赵海京
张秀媛
倪青
桂建华
ZHAO Haijing;ZHANG Xiuyuan;NI Qing;GUI Jianhua(Department of Endocrinology,Shunyi District Hospital of Beijing University of Traditional Chinese Medicine,Beijing 101300,China;Traditional Chinese medicine,Beijing University of Chinese Medicine,Beijing 101300,China;Guanganmen Hospital,Chinese Academy of Traditional Chinese Medicine,Beijing 100053,China)
出处
《世界中医药》
CAS
2021年第2期307-310,共4页
World Chinese Medicine
基金
首都卫生发展科研专项项目(2016-1-4151)。
关键词
糖尿病肾病
调理脾胃针法
综合营养干预
血糖
肾功能
保护作用
Diabetic nephropathy
Regulating spleen and stomach acupuncture
Integrated nutrition intervention
Blood glucose
Renal function
Protective effect
