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A discovery of low hydraulic resistance channels along meridians in rats 被引量:1

大鼠循经低流阻通道的发现
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摘要 Background:Continuous and porous low hydraulic resistance channels(LHRCs)are important structures of meridians in traditional Chinese medicine(TCM).In this study,based on the previous research on LHRCs along meridian paths(LHRCMs)in mini-pig,we aimed to detect the low hydraulic resistance point(LHRP)and display the LHRCMs in rats.Methods:A technique for measuring interstitial hydraulic resistance(Rh)in rats was established to detect and measure the Rh along the conception vessel(CV)in TCM,and Alcian Blue(AB)solution was injected into the LHRP along the CV.The interstitial fluid pressure(IFP)of the LHRP was measured before and after AB injection.Then,the distribution characteristics of the AB solution were investigated to explore the relationship between AB tracks and meridian paths in TCM.Results:The positions of the LHRPs coincided with the low impedance points(LIPs)of the rat skin along the CV.The Rh value along the CV(10.37,1.26,×10^(6)dyne s cm^(-5))was significantly lower than that in the non-meridian area(19.13±1.37,×10^(6)dyne s cm^(-5),P<0.01).After AB injection,the IFP of the LHRP was 2.52 mmHg,which was higher than that before AB injection.The AB tracks(ABT)along the CV,spleen meridian,and kidney meridian appeared in one or two directions,with single or multiple paths and uneven thickness and length.The appearance rate was 73.33%.Conclusions:LHRCMs existed not only in minipigs but also in rats.The LHRCMs could be observed after AB injection into the LHRP in the subcutaneous connective tissues of rats.
作者 Xiao-jing SONG Wei-bo ZHANG Shu-yong JIA Guang-jun WANG Shu-you WANG Hong-yan LI Feng XIONG 宋晓晶;张维波;贾术永;王广军;王淑友;李宏彦;熊枫(中国中医科学院针灸研究所,中国北京100700)
出处 《World Journal of Acupuncture-Moxibustion》 CSCD 2021年第1期22-29,共8页 世界针灸杂志(英文版)
基金 the Fundamental Research Funds for the Central Public Welfare Research Institutes:ZZ 20191606 National Natural Science Foundation of China:82050006。
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