摘要
通过文献评阅,总结不同国家的疫苗安全监测系统建设与管理经验,并对我国加强疫苗监测系统管理提出建议。研究发现众多国家或地区疫苗监测系统如美国疫苗不良事件报告系统(VAERS)、EudraVigilance等能多部门联合监测、对不良信号进行分析总结、提高国民主动报告意识,以此保障不同地区疫苗安全;但不少监测系统仍存在报告偏倚、系统分散等不足之处。我国疫苗监测系统应吸取国际经验和教训,建立多部门联合、能主动监测、对公众开放的全面高效的疫苗监测系统,保证疫苗安全。
We summarized the experiences of construction and management of vaccine safety surveillance systems in different countries and regions by using literature review,and then made the recommendations of strengthening vaccine surveillance system in China.In the study,we found that multiple existing national and regional vaccine surveillance systems,such as VAERS and EudraVigilance,can ensure vaccine safety through multi-sectoral surveillance,identification of adverse signals,and promotion of awareness of active reporting.However,the monitoring systems have some limitations,such as reporting bias and system decentralization.Therefore,China’s vaccine monitoring system should establish an effective vaccine surveillance system,which achieves multi-sectoral,active,open to the public surveillance.
作者
徐芳
刘爽
严非
王伟
阿克忠
付朝伟
XU Fang;LIU Shuang;YAN Fei;WANG Wei;A Ke-zhong;FU Chao-wei(School of Public Health,Fudan University,Global Health Institute,National Key Laboratory of Health Technology Assessment of Ministry of Health,Shanghai 200032,China;Qinghai Provincial Center for Disease Control and Prevention,Xining,Qinghai 810007,China)
出处
《上海预防医学》
CAS
2021年第1期73-78,共6页
Shanghai Journal of Preventive Medicine
基金
健康中国2030背景下的中国疫苗市场准入与管理研究项目。
关键词
疫苗
监测系统
疫苗安全
vaccine
surveillance system
vaccine safety
