摘要
目的探讨急性脑梗死患者左房扩大发生率,并分析左房扩大的危险因素。方法选取2014年1月至2018年11月任丘康济新图医院神经内科收治的急性脑梗死患者1030例,进行问卷调查、人体测量、实验室检查、心脏超声检查。根据心脏彩超左房内径指数(left atrial diameter indexed to height,LADI)分为左房正常组(LADI≤24 mm/m,827例)和左房扩大组(LADI>24 mm/m,203例),采用多元logistic回归分析急性脑梗死患者左房扩大的相关危险因素。结果左房正常组与左房扩大组在年龄、BMI、心房颤动、冠心病、吸烟、过量饮酒、胱抑素C、SCr、尿酸、左室质量指数比较,差异有统计学意义(P<0.05);多因素logistic回归分析显示,年龄(OR=1.054,95%CI:1.034~1.074,P=0.000)、BMI(OR=1.142,95%CI:1.084~1.204,P=0.000)、心房颤动(OR=12.960,95%CI:6.843~24.546,P=0.000)、冠心病(OR=1.785,95%CI:1.194~2.670,P=0.005)、吸烟(OR=2.033,95%CI:1.354~3.053,P=0.001)、过量饮酒(OR=3.511,95%CI:1.585~7.777,P=0.002)、左室质量指数(OR=1.028,95%CI:1.021~1.035,P=0.000)为急性脑梗死患者左房扩大的独立危险因素。结论急性脑梗死患者左房扩大与年龄、BMI、心房颤动、冠心病、吸烟、过量饮酒、左室质量指数密切相关,有效控制体质量,积极进行有氧运动,戒烟、戒酒,控制心房颤动可延缓左房扩大,减少心脑血管病的发生。
Objective To investigate the incidence of left atrium enlargement in patients with acute cerebral infarction,and to analyze the risk factors of the expansion of left atrial.Methods A total of 1030 patients with acute cerebral infarction admitted to the Department of Neurology,Renqiu Kangji Xintu Hospital from January 2014 to November 2018 were included.Body health questionnaire survey,laboratory tests and echocardiography were conducted.According to left atrial diameter indexed to height(LADI)values patients were divided into normal left atrial group(LADI≤24 mm/m,827 cases)and enlarged left atrial group(LADI>24 mm/m,203 cases).Multivariate logistic regression was used to analyze the risk factors of left atrium enlargement in patients with acute cerebral infarction.Results Between the normal left atrial group and the enlarged left atrial group,age,BMI,atrial fibrillation,coronary heart disease,smoking,excessive drinking,cystatin C,SCr,uric acid and left ventricular mass index showed significant differences.After adjusting potential confounders,age(OR=1.054,95%CI:1.034-1.074,P=0.000),BMI(OR=1.142,95%CI:1.084-1.204,P=0.000),atrial fibrillation(OR=12.960,95%CI:6.843-24.546,P=0.000),coronary heart disease(OR=1.785,95%CI:1.194-2.670,P=0.005),smoking(OR=2.033,95%CI:1.354-3.053,P=0.001),excessive drinking(OR=3.511,95%CI:1.585-7.777,P=0.002),left ventricular mass index(OR=1.028,95%CI:1.021-1.035,P=0.000)were shown to be significantly associated with left atrium enlargement in patients with acute cerebral infarction.Conclusions The enlargement of left atrial in patients with acute cerebral infarction is closely related to age,BMI,atrial fibrillation,coronary heart disease,smoking,excessive drinking and left atrial mass index.Effective weight control,active promotion of aerobic exercise,abstinence,control of atrial fibrillation maybe delay the enlargement of left atrium,further reduce the incidence of cardiovascular and cerebrovascular diseases.
作者
朱东磊
高素颖
李芳
于凯
刘东亮
冀瑞俊
王拥军
Zhu Donglei;Gao Suying;Li Fang;Yu Kai;Liu Dongliang;Ji Ruijun;Wang Yongjun(Department of Cardiology,Wenan Kangji Hospital,Langfang 065800,China)
出处
《北京医学》
CAS
2020年第12期1174-1177,共4页
Beijing Medical Journal
关键词
急性脑梗死
左房内径指数
左房扩大
危险因素
acute cerebral infarction
left atrial diameter indexed to height(LADI)
left atrium enlargement
risk factor
