摘要
目的:为临床合理使用注射用哌拉西林钠他唑巴坦钠提供参考。方法:以注射用哌拉西林钠他唑巴坦钠说明书为基础,依据《抗菌药物临床应用指导原则》(2015年版),参照相关文献及规范,建立基于加权优劣解距离法(TOPSIS)的哌拉西林钠他唑巴坦钠药物利用评价细则,以此为依据,对某院2018年11-12月共140例患者哌拉西林钠他唑巴坦钠的使用情况进行评价。结果:评价的140份病历中,与最优方案接近程度(Ci)大于80%的50例(占比35.7%),Ci在70%~80%的20例(占比14.3%),Ci在60%~70%的70例(占比50.0%)。结论:基于加权TOPSIS法的哌拉西林钠他唑巴坦钠的药物利用评价方法可用于其药物利用评价。评价结果显示该院哌拉西林钠他唑巴坦钠使用较为合理,但医院需在处方权限、给药剂量和给药间隔等方面进一步规范哌拉西林钠他唑巴坦钠的合理使用。
OBJECTIVE To provide references for rational use of piperacillin sodium and tazobactam sodium for injection.METHODS Based upon package insert, guiding principles for clinical application of antibacterials(2015 Edition), related literatures and specifications and the weighted TOPSIS method, the evaluation criteria of piperacillin sodium and tazobactam sodium for injection were formulated for assessing use of piperacillin sodium and tazobactam sodium for injection in 140 inpatients from November 2018 to December 2018.RESULTS Among a total of 140 cases, relative proximity was >80%(n=50, 35.7%), 70%-80%(n=20, 14.3%) and 60%-70%(n=70, 50.0%).CONCLUSION It is reasonable and feasible to adopt weighted TOPSIS as drug use evaluation method for piperacillin sodium and tazobactam sodium for injection. Use of piperacillin sodium tazobactam sodium is reasonable. However, its rational use should be further standardized in terms of prescription authority, dosage and interval.
作者
王桂凤
刘锐锋
李雪芹
李运景
WANG Gui-feng;LIU Rui-feng;LI Xue-qin;LI Yun-jing(Department of Pharmacy,Zhongshan Municipal Peopled Hospital,Guangdong Zhongshan 528403,China)
出处
《中国医院药学杂志》
CAS
北大核心
2021年第1期52-56,共5页
Chinese Journal of Hospital Pharmacy
基金
中山市科技局课题(编号:2018B1093)。
关键词
加权TOPSIS法
药物利用评价
哌拉西林钠他唑巴坦钠
属性层次模型
weighted TOPSIS method
drug use evaluation
piperacillin sodium and tazobactam sodium for injection
attribute hierarchical model
