摘要
目的探讨认知行为综合干预对恶性黑色素瘤患者心理健康及遵医行为的影响。方法按照随机数字表法、单盲原则将160例恶性黑色素瘤患者分为观察组和对照组各80例,对照组患者接受常规干预,观察组患者接受认知行为综合干预。采用焦虑自评量表(SAS)和抑郁自评量表(SDS)评估两组患者的心理健康状态;采用遵医行为量表评估两组患者的遵医行为;采用生活质量综合评定问卷-74(GQOL-74)评估两组患者的生活质量;比较两组患者的不良反应发生情况。结果干预后,两组患者SAS、SDS评分均明显低于本组干预前,GQOL-74量表各维度评分均明显高于本组干预前;且观察组患者SAS、SDS评分均明显低于对照组患者,GQOL-74量表各维度评分均明显高于对照组患者,差异均有统计学意义(P﹤0.01)。干预后,观察组患者遵医行为均优于本组干预前和对照组患者,差异均有统计学意义(P﹤0.05)。观察组患者的不良反应总发生率为7.50%,低于对照组患者的21.25%,差异有统计学意义(P﹤0.05)。结论认知行为综合干预有利于改善恶性黑色素瘤患者的负性情绪,提高遵医行为和生活质量,同时降低药物不良反应的发生率。
Objective To explore the effect of comprehensive intervention of cognitive behavior on the mental health and compliance behavior of patients with malignant melanoma.Method 160 patients with malignant melanoma were divided into observation group(n=80,treated with comprehensive cognitive behavioral intervention)and control group(n=80,treated with conventional intervention)according to random number and single blind.Self-rating anxiety scale(SAS)and self-rating depression scale(SDS)were used to evaluate the mental health,compliance evaluated by compliance behavior scale,quality of life evaluated by the generic quality of life inventory-74(GQOL-74),and adverse reactions compared between the two groups.Result After the intervention,the SAS and SDS scores of the two groups of patients were significantly lower than those of the group before the intervention,and the scores of all dimensions of the GQOL-74 scale were significantly higher than those of the group before the intervention;and the SAS and SDS scores of the observation group were significantly lower than those of control group,the scores of all dimensions of the GQOL-74 scale were significantly higher than those of control group,and the differences were statistically significant(P<0.01).After the intervention,the compliance behaviors of patients in the observation group were better than those in the pre-intervention and control groups,and the differences were statistically significant(P<0.05).The total incidence of adverse reactions in the observation group was 7.50%,which was lower than 21.25%in the control group,the difference was statistically significant(P<0.05).Conclusion Comprehensive cognitive behavioral intervention is beneficial to improve the negative emotion,improve the compliance and quality of life,and reduce the incidence of adverse reactions of patients with malignant melanoma.
作者
黄蕊
张芳芳
张蕾
HUANG Rui;ZHANG Fangfang;ZHANG Lei(Department of Dermatology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,He’nan,China)
出处
《癌症进展》
2021年第3期317-320,共4页
Oncology Progress
关键词
认知行为综合干预
恶性黑色素瘤
心理健康
遵医行为
comprehensive cognitive behavioral intervention
malignant melanoma
mental health
compliance
